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Autor:
Pritmohinder S. Gill, Xi Yang, Laura K. Schnackenberg, Jinchun Sun, Richard D. Beger, Laura P. James, Sudeepa Bhattacharyya
Publikováno v:
Archives of Toxicology
Acetaminophen (APAP) is a commonly used analgesic drug that can cause liver injury, liver necrosis and liver failure. APAP-induced liver injury is associated with glutathione depletion, the formation of APAP protein adducts, the generation of reactiv