Zobrazeno 1 - 10
of 133
pro vyhledávání: '"35"'
Autor:
Kenneth K. Wu, Pei-Feng Chen
Publikováno v:
Archives of Biochemistry and Biophysics. 486:132-140
Human endothelial nitric-oxide synthase (eNOS) is a complex enzyme, requiring binding of calmodulin (CaM) for electron transfer. The prevailing view is that calcium-activated CaM binds eNOS at the canonical binding site located at residues 493-510, w
Autor:
Nancy Burton-Wurster, George Lust
Publikováno v:
Archives of Biochemistry and Biophysics. 306:309-320
Fibronectin heterogeneity is, in part, the result of post-translational modifications. In these experiments, cartilage fibronectins were purified by anion exchange chromatography, followed by gelatin affinity chromatography or immunoprecipitation, an
Publikováno v:
Archives of Biochemistry and Biophysics. 284:63-70
An earlier report from this laboratory documented a substantial increase in the rates of dolichol-linked oligosaccharide intermediate synthesis and protein N-glycosylation in purified murine splenic B lymphocytes (B cells) activated by treatment with
Publikováno v:
Archives of biochemistry and biophysics. 374(2)
c-MycS proteins are truncated forms of the transcription factor which have been shown to be produced by translation initiation at internal methionines (101, 121, and 134) and to be functional in the regulation of gene expression, cell proliferation,
Autor:
Gene C. Ness, Christopher M. Chambers
Publikováno v:
Archives of biochemistry and biophysics. 354(2)
The level of gene expression at which dietary cholesterol exerts feedback regulation on hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase was investigated using young male Sprague–Dawley rats. Previous studies suggested that this re
Publikováno v:
Archives of biochemistry and biophysics. 338(1)
The male-specific P450 enzyme CYP 2C11, whose expression is developmentally and hormonally regulated, is the major steroid 16α-hydroxylase of the untreated rat liver. The enzyme metabolizes a host of substrates, including mechanism-based inactivator
Publikováno v:
Archives of biochemistry and biophysics. 312(2)
Synthesis of the large dermatan sulfate (DS) proteoglycan by rat ovarian granulosa cells was studied using metabolic radiolabel precursors in culture media with varying concentrations of environmental sulfate (20-800 μM) and cysteine (130 and 650 μ
Publikováno v:
Archives of biochemistry and biophysics. 308(1)
The effects of basic fibroblast growth factor (bFGF) and insulin-like growth factor-I (IGF-I) on cell and matrix metabolism in calf and adult bovine cartilage explants were examined. In calf cartilage, bFGF elicited dose-dependent and bi-directional
Publikováno v:
Archives of Biochemistry and Biophysics. 689:108429
Lysine is a precursor for desferrioxamine siderophore biosynthesis. The pathway is often initiated by lysine decarboxylases. However, little is known about those enzymes from Actinobacteria which represents a diverse class of desferrioxamine producer
Autor:
Raymond L. Ward
Publikováno v:
Archives of Biochemistry and Biophysics. 169:22-28
35 Cl nmr relaxation rate measurements have been used to study anion-binding sites in pig heart lactate dehydrogenase. These studies reveal two types of sites, one is intimately associated with the active site, the other is not. The nonactive site ha