Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sonia, Burrel"'
Autor:
Hélène Guermouche, Olivier Rogier, Jean-Michel Pawlotsky, Sonia Burrel, David Boutolleau, Mélanie Mercier-Darty, Christophe Rodriguez, Thomas Kofman
Publikováno v:
Antiviral Research
Antiviral Research, Elsevier Masson, 2020, 173, pp.104647-. ⟨10.1016/j.antiviral.2019.104647⟩
Antiviral Research, Elsevier Masson, 2020, 173, pp.104647-. ⟨10.1016/j.antiviral.2019.104647⟩
International audience; Prophylactic or preemptive treatment strategies are required to prevent human cytomegalovirus (CMV) infections in transplant recipients. However, treatment failure occurs when CMV resistant-associated variants (RAVs) are selec
Autor:
David Boutolleau, Christel Brunet, Sonia Burrel, Marianne Collot, Caroline Rouard, Henri Agut
Publikováno v:
Antiviral Research. 128:1-6
The emergence of herpes simplex virus (HSV) resistance to current antiviral drugs, that all target the viral DNA polymerase, constitutes a major obstacle to antiviral treatment effectiveness of HSV infections, especially in immunocompromised patients
Publikováno v:
Antiviral Research. 111:8-12
Currently approved anti-human cytomegalovirus (CMV) drugs, all targeting the viral DNA polymerase, are associated with significant toxicities and emergence of drug resistance. In this context, CMV terminase complex constitutes a promising target for
Autor:
Sonia Burrel, Catherine Aime, Laurence Hermet, David Boutolleau, Henri Agut, Zaina Ait-Arkoub
Publikováno v:
Antiviral Research. 100:365-372
Herpes simplex virus (HSV) resistance to antivirals constitutes a therapeutic challenge, especially among immunocompromised patients. This observational survey on HSV resistance to antivirals was conducted retrospectively over a 4-year period (2008
Publikováno v:
Antiviral Research. 91:32-35
The molecular mechanisms of human cytomegalovirus (CMV) resistance to both ganciclovir and maribavir reported so far rely predominantly on the presence of mutations within UL97 phosphotransferase. The accurate interpretation of genotypic antiviral re
Autor:
Bruno Lina, Jean-Sébastien Casalegno, Mauricette Michallet, Viviane Nave, Sonia Burrel, F. Morfin, Geneviève Billaud, Emilie Frobert, Sophie Ducastelle-Lepretre, Florence Ader, David Boutolleau
Publikováno v:
Antiviral research. 111
The widespread use of acyclovir (ACV) and the increasing number of immunocompromised patients have raised concern about an increase in ACV-resistant herpes simplex virus (HSV). ACV resistance has traditionally been a major concern for immunocompromis
Publikováno v:
Antiviral research. 96(3)
The acyclic analogue of guanosine acyclovir (ACV) constitutes the first-line drug for the treatment of herpes simplex virus (HSV) infections. ACV activation requires primophosphorylation by virus-encoded HSV thymidine kinase (TK). In 95% of cases, HS
Publikováno v:
Antiviral research. 93(1)
The herpes simplex virus (HSV) DNA polymerase is composed of the UL30 catalytic subunit and the UL42 processivity factor. The UL42 subunit increases the processivity of the polymerase along the DNA template during replication. The molecular mechanism