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Publikováno v:
Antioxidants, Vol 13, Iss 6, p 679 (2024)
Statins are 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductase inhibitors widely used in the treatment of hyperlipidemia. The inhibition of HMG-CoA reductase in the mevalonate pathway leads to the suppression of cell proliferation and inductio
Externí odkaz:
https://doaj.org/article/13bdc474a470471d975d7e67e272be7f
Autor:
Chen-Yen Chien, Ting-Jui Wen, Yu-Hsiuan Cheng, Yi-Ting Tsai, Chih-Yao Chiang, Chiang-Ting Chien
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 679 (2020)
Diabetes exacerbates myocardial ischemia/reperfusion (IR) injury by incompletely understood mechanisms. We explored whether diabetes diminished BAG3/Bcl-2/Nrf-2/HO-1-mediated cardioprotection and overproduced oxidative stress contributing to exaggera
Externí odkaz:
https://doaj.org/article/d690e064f02842ba8fb941bf6402ac4c