Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Catherine Li"'
Publikováno v:
Antimicrob Agents Chemother
In 2018, the U.S. Food and Drug Administration (FDA) issued a Drug Safety Communication regarding fluoroquinolone-associated aortic aneurysm. This quasi-experimental study assessed antibiotic prescribing for 198 patients hospitalized with diabetic fo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Bisphosphonates are widely used for the treatment of bone disorders. These drugs also inhibit the growth of a variety of protozoan parasites, such as Toxoplasma gondii, the etiologic agent of toxoplasmosis. The target of the most potent bisphosphonat
Autor:
Zhu-Hong Li, Silvia N.J. Moreno, Catherine Li, Boris Striepen, Nathan M. Howell, Maria Noelia Chao, Tamila Pavlivna Galaka, Sergio H. Szajnman, Juan B. Rodriguez, Vasant Muralidharan
Publikováno v:
Antimicrobial agents and chemotherapy. 61(2)
We tested a series of sulfur-containing linear bisphosphonates against Toxoplasma gondii , the etiologic agent of toxoplasmosis. The most potent compound (compound 22; 1-[( n -decylsulfonyl)ethyl]-1,1-bisphosphonic acid) is a sulfone-containing compo
Autor:
David Sept, Karl A. Werbovetz, Roxanna J. Ochoa, Naomi S. Morrissette, Catherine Li, Johnson Q. Tran, Christopher I. Ma, Frank Gu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:1453-1460
The human parasite Toxoplasma gondii is sensitive to dinitroaniline compounds which selectively disrupt microtubules in diverse protozoa but which have no detectable effect on vertebrate host cell microtubules or other functions. Replication of wild-
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:309-316
A high-throughput growth assay for the protozoan parasiteToxoplasma gondiiwas developed based on a highly fluorescent transgenic parasite line. These parasites are stably transfected with a tandem yellow fluorescent protein (YFP) and are 1,000 times