Zobrazeno 1 - 9
of 9
pro vyhledávání: '"59"'
Autor:
Christelle M. Roux, Carlos Leon, Briana M. Young, Renée M. Tsolis, Vidya L. Atluri, Maria G. Winter, Lisa Tran, Tobias Kerrinnes
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 11
Kerrinnes, T; Young, BM; Leon, C; Roux, CM; Tran, L; Atluri, VL; et al.(2015). Phospholipase A1 modulates the cell envelope phospholipid content of brucella melitensis, contributing to polymyxin resistance and pathogenicity. Antimicrobial Agents and Chemotherapy, 59(11), 6717-6724. doi: 10.1128/AAC.00792-15. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0w34d8s5
Kerrinnes, T; Young, BM; Leon, C; Roux, CM; Tran, L; Atluri, VL; et al.(2015). Phospholipase A1 modulates the cell envelope phospholipid content of brucella melitensis, contributing to polymyxin resistance and pathogenicity. Antimicrobial Agents and Chemotherapy, 59(11), 6717-6724. doi: 10.1128/AAC.00792-15. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0w34d8s5
A subset of bacterial pathogens, including the zoonotic Brucella species, are highly resistant against polymyxin antibiotics. Bacterial polymyxin resistance has been attributed primarily to the modification of lipopolysaccharide; however, it is unkno
Autor:
A. Fabrice Some, Paul Milligan, François Nosten, Issaka Zongo, Philip J. Rosenthal, Colin J. Sutherland, Jean-Bosco Ouédraogo, Brian Greenwood, Yves Daniel Compaoré, Joel Tarning
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 8
The WHO recommends that children living in areas of highly seasonal malaria transmission in the Sahel subregion should receive seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ). We evaluated the use of dihy
Autor:
Donald G. Catanzaro, Nazir Ahmed Ismail, Francine Arroyo, Thomas C. Victor, Kathleen D. Eisenach, Duylinh Nguyen, Timothy C. Rodwell, Camilla Rodrigues, Shou-Yean Grace Lin, Janice Kaping, Richard S. Garfein, Kanchan Ajbani, Valeru Crudu, Edward Desmond, Antonino Catanzaro, Maria Tarcela Gler, Lynn Jackson
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 1
Ajbani, K; Lin, SYG; Rodrigues, C; Nguyen, D; Arroyo, F; Kaping, J; et al.(2015). Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries. Antimicrobial Agents and Chemotherapy, 59(1), 414-420. doi: 10.1128/AAC.03614-14. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3rr5v7v8
Ajbani, K; Lin, SYG; Rodrigues, C; Nguyen, D; Arroyo, F; Kaping, J; et al.(2015). Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries. Antimicrobial Agents and Chemotherapy, 59(1), 414-420. doi: 10.1128/AAC.03614-14. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3rr5v7v8
Reliable molecular diagnostics, which detect specific mutations associated with drug resistance, are promising technologies for the rapid identification and monitoring of drug resistance in Mycobacterium tuberculosis isolates. Pyrosequencing (PSQ) ha
Autor:
Jason W. Chien, Laurel J. Gershwin, Anne Carey, Richard L. Mackman, Eugene J. Eisenberg, Michel Perron, Sandy Lewis, Robert Jordan, Heather A. McEligot, Robert G. Strickley, Mark L Anderson, Nicole E. Behrens, Matt X. Shao, Tomas Cihlar
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 8
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and pneumonia in infants. Effective treatment for RSV infection is a significant unmet medical need. While new RSV therapeutics are now in development, there are very few animal
Autor:
Mary E. Moreno, Michael Murphey-Corb, Stefan G. Sarafianos, Jose M. Rivera, Barbara Sloan, Cheryl A. Stoddart, Galina Kosikova, Pheroze Joshi, Michael A. Parniak, Sofiya A. Galkina, Aaron B. Reeve
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 7
Like normal cellular nucleosides, the nucleoside reverse transcriptase (RT) inhibitor (NRTI) 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) has a 3′-hydroxyl moiety, and yet EFdA is a highly potent inhibitor of human immunodeficiency virus (HIV)
Autor:
Zachary Herrera, Wesley Wu, Joseph L. DeRisi, Seok H. Cho, Katie Baska, Ellen Yeh, Danny Ebert
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 1
The apicoplast is an essential plastid organelle found in Plasmodium parasites which contains several clinically validated antimalarial-drug targets. A chemical rescue screen identified MMV-08138 from the “Malaria Box” library of growth-inhibitor
Autor:
Caroline Nguyen, Alice Zhou, Pamela J. Yeh, Minh Quan Nguyen, Tina Manzhu Kang, Casey Beppler, Jessica Yuan, Jeffrey H Miller, Zhiyuan Mao
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 1
Gram-negative bacteria are normally resistant to the antibiotic vancomycin (VAN), which cannot significantly penetrate the outer membrane. We used Escherichia coli mutants that are partially sensitive to VAN to study synergies between VAN and 10 othe
Autor:
Jeffrey N. Martin, Art F. Y. Poon, Winnie Dong, Guinevere Q. Lee, Chanson J. Brumme, A. R. Mocello, A. Karakas, David R. Bangsberg, Hope R. Lapointe, P. R. Harrigan, Yap Boum, Don Kirkby
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 11
Limited access to HIV drug resistance testing in low- and middle-income countries impedes clinical decision-making at the individual patient level. An efficient protocol to address this issue must be established to minimize negative therapeutic outco
Autor:
Philip J. Rosenthal, Roland A. Cooper, Samuel L. Nsobya, Melissa D. Conrad, Jessica Bloome, Benjamin Kozak, Moses R. Kamya, Diane V. Havlir, Abel Kakuru, Oswald Byaruhanga, Victor Bigira, Jiri Gut, Jennifer Legac, Norbert P. LeClair, Bryan Greenhouse, James Kapisi, Jaffer Okiring, Grant Dorsey, Patrick K Tumwebaze, Andrew Walakira, Christine Nakazibwe
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 6
Changing treatment practices may be selecting for changes in the drug sensitivity of malaria parasites. We characterized ex vivo drug sensitivity and parasite polymorphisms associated with sensitivity in 459 Plasmodium falciparum samples obtained fro