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Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:1017-1022
This study investigated macrolide resistance mechanisms in clinical Haemophilus influenzae strains with different levels of susceptibility to macrolides. A total of 6,382 isolates were collected during the Alexander Project from 1997 to 2000. For 96.
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:4447-4449
Ethambutol (EMB) [(S,S′)-2,2′-(ethylenediimino)di-1-butanol] is a first-line drug used for antituberculosis therapy. It is often used in combination with isoniazid, rifampin, pyrazinamide, and streptomycin. Membrane-associated arabinosyl transfer
Publikováno v:
Antimicrobial agents and chemotherapy. 39(11)
Resistance to isoniazid in Mycobacterium tuberculosis has been associated with mutations in genes encoding the mycobacterial catalase-peroxidase (katG) and the InhA protein (inhA). Among the 26 isoniazid-resistant clinical isolates evaluated in this