Zobrazeno 1 - 10
of 15
pro vyhledávání: '"11"'
Autor:
Laura J. V. Piddock, Mark A. Webber
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:1550-1552
The amount of acrB, marA , and soxS mRNA was determined in 36 fluoroquinolone-resistant E. coli from humans and animals, 27 of which displayed a multiple-resistance phenotype. acrB mRNA was elevated in 11 of 36 strains. A mutation at codon 45 (Arg→
Autor:
Mitsuo Kaku, Yoshikuni Onodera, Shinichiro Yamachika, Kenichi Sato, Tomoo Saga, Hiroyuki Takase
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:2144-2145
The gene qnr (qnrA [G. A. Jacoby, K. Walsh, D. Mills, V. Walker, A. Robicsek, H. Oh, and D. C. Hooper, Abstr. 44th Intersci. Conf. Antimicrob. Agents Chemother., abstr. C2-1898a, 2004]; encoding QnrA) was first identified as a transferable quinolone
Autor:
Peter M. Keller, Marcel Yotebieng, Chloé Loiseau, Erik C. Böttger, Kathrin Zürcher, Robert J. Wilkinson, Sonia Borrell, Matthias Egger, Miriam Reinhard, Jimena Collantes, Anchalee Avihingsanon, Peter Sander, Lukas Fenner, Martina L. Reichmuth, Sebastien Gagneux, Rico Hömke
Publikováno v:
Antimicrobial Agents and Chemotherapy
Reichmuth, Martina L.; Hömke, Rico; Zürcher, Kathrin; Sander, Peter; Avihingsanon, Anchalee; Collantes, Jimena; Loiseau, Chloé; Borrell, Sonia; Reinhard, Miriam; Wilkinson, Robert J; Yotebieng, Marcel; Fenner, Lukas; Böttger, Erik C; Gagneux, Sebastien; Egger, Matthias; Keller, Peter Michael (2020). Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-naïve Patients. Antimicrobial agents and chemotherapy, 64(11), e00513-20. American Society for Microbiology 10.1128/AAC.00513-20
Reichmuth, Martina L.; Hömke, Rico; Zürcher, Kathrin; Sander, Peter; Avihingsanon, Anchalee; Collantes, Jimena; Loiseau, Chloé; Borrell, Sonia; Reinhard, Miriam; Wilkinson, Robert J; Yotebieng, Marcel; Fenner, Lukas; Böttger, Erik C; Gagneux, Sebastien; Egger, Matthias; Keller, Peter Michael (2020). Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-naïve Patients. Antimicrobial agents and chemotherapy, 64(11), e00513-20. American Society for Microbiology 10.1128/AAC.00513-20
Mutations in the genes of the F420 signaling pathway of Mycobacterium tuberculosis complex, including dnn, fgd1, fbiA, fbiB, fbiC, and fbiD, can lead to delamanid resistance. We searched for such mutations among 129 M. tuberculosis strains from Asia,
Autor:
Haihong Hao, Jun Li, Abdul Sajid, Heying Zhang, Zonghui Yuan, Jianan Ning, Muhammad Abu Bakr Shabbir, Guyue Cheng, Menghong Dai
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
This study aimed to investigate the genetic characteristics, antibiotic resistance patterns, and novel mechanisms involved in fluoroquinolone (FQ) resistance in commensal Escherichia coli isolates. The E. coli isolates were recovered from a previous
Autor:
Tomoiku Takaku, Henry F. Chambers, Yuki Katayama, Norio Komatsu, Motoyasu Miyazaki, Hideaki Hanaki, Hidehito Matsui, Tomonori Ochiai, Takuya Azechi, Tohru Takata, Kota Asakura, Koji Yahara, Hiroshi Sasano, Miwa Sekine
Publikováno v:
Antimicrobial agents and chemotherapy, vol 61, iss 11
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy
We previously reported a novel phenotype of vancomycin-intermediate Staphylococcus aureus (VISA), i.e., “slow VISA,” whose colonies appear only after 72 h of incubation. Slow-VISA strains can be difficult to detect because prolonged incubation is
Autor:
Vegard Eldholm, Abigail L. Manson, Alexander Pym, Kashmeel Maharaj, Lynne de Welzen, Ashlee M. Earl
Publikováno v:
Antimicrobial Agents and Chemotherapy
Genetics-based drug susceptibility testing has improved the diagnosis of drug-resistant tuberculosis but is limited by our lack of knowledge of all resistance mechanisms. Next-generation sequencing has assisted in identifying the principal genetic me
Autor:
David C. Samuels, Fernanda Maruri, Amondrea Blackman, Timothy R. Sterling, Brandon Eilertson, Miguel Herrera
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:3270-3275
Heteroresistance is the coexistence of populations with differing nucleotides at a drug resistance locus within a sample of organisms. Although Sanger sequencing is the gold standard for sequencing, it may be less sensitive than deep sequencing for d
Autor:
Ronald N. Jones, Sarah E. Farrell, Rodrigo E. Mendes, Mariana Castanheira, Lalitagauri M. Deshpande
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:3012-3020
Enterobacteriaceae bacteremia isolates ( n = 195; 6.4% overall) collected from 26 U.S. hospitals located in 20 states were screened for various β-lactamase classes. A total of 175 isolates carried one to eight acquired β-lactamase genes of 44 types
Autor:
Alexander A. Neyfakh, Maria J. Gomez
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:3562-3567
Bacterial genes defining intrinsic resistance to antibiotics encode proteins that can be targeted by antibiotic potentiators. To find such genes, a transposon insertion library of Acinetobacter baylyi was screened with subinhibitory concentrations of
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:2089-2094
The contribution of regulatory genes to fluoroquinolone resistance was studied with clinical Escherichia coli strains bearing mutations in gyrA and parC and with different levels of fluoroquinolone resistance. Expression of marA and soxS was evaluate