Zobrazeno 1 - 10
of 26
pro vyhledávání: '"11"'
Autor:
Robert F. Dannals, Alvaro A. Ordonez, Zhuo Zhang, Sanjay K. Jain, Hui Wang, Vincent P. DeMarco, Peter J. Tonge, Edward A. Weinstein, Carlton K. K. Lee, Véronique Dartois, Kelly E. Dooley, Daniel P. Holt, Brendan Prideaux, Mariah H. Klunk
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Autor:
Robert F. Dannals, Alvaro A. Ordonez, Hui Wang, Brendan Prideaux, Sanjay K. Jain, Véronique Dartois, Carlton K. K. Lee, Daniel P. Holt, Peter J. Tonge, Kelly E. Dooley, Edward A. Weinstein, Zhang Zhuo, Vincent P. DeMarco, Mariah H. Klunk
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:5768-5774
Information about intralesional pharmacokinetics (PK) and spatial distribution of tuberculosis (TB) drugs is limited and has not been used to optimize dosing recommendations for new or existing drugs. While new techniques can detect drugs and their m
Autor:
Laura McEntee, William W. Hope, Aaron Dane, Akash Jain, Jennifer Unsworth, Ian A. Critchley, Nicola Farrington, Shampa Das, Nicole Cotroneo, David Melnick, Adam Johnson, Thomas R. Parr, Paul G. Ambrose
Publikováno v:
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Tebipenem pivoxil HBr (TBPM-PI-HBr) is a novel orally bioavailable carbapenem. The active moiety is tebipenem. Tebipenem pivoxil is licensed for use in Japan in children with ear, nose, and throat infections and respiratory infections. The HBr salt w
Autor:
Marguerite L. Monogue, Masakatsu Tsuji, Roger Echols, Sean M. Stainton, David P. Nicolau, Yoshinori Yamano
Publikováno v:
Antimicrobial Agents and Chemotherapy
Herein, we evaluated sustainability of humanized exposures of cefiderocol in vivo over 72 h against pathogens with cefiderocol MICs of 0.5 to 16 μg/ml in the neutropenic murine thigh model. In Acinetobacter baumannii, Pseudomonas aeruginosa, and Ent
Autor:
Philippe M. Loiseau, Madeleine Besnard, Cécile Menez, Robert Farinotti, Gillian Barratt, Marion Buyse
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2006, 50, pp.3793-3800. ⟨10.1128/AAC.00837-06⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2006, 50, pp.3793-3800. ⟨10.1128/AAC.00837-06⟩
The aim of this study was to evaluate the potential of a combination of two antileishmanial drugs, miltefosine (HePC) and amphotericin B (AMB), when administered by the oral route. Caco-2 cell monolayers were used as a validated in vitro model of the
Publikováno v:
Antimicrobial Agents and Chemotherapy, 56, 11, pp. 6054-6
Antimicrobial Agents and Chemotherapy, 56(11), 6054-6056. American Society for Microbiology
Antimicrobial Agents and Chemotherapy, 56, 6054-6
Antimicrobial Agents and Chemotherapy, 56(11), 6054-6056. American Society for Microbiology
Antimicrobial Agents and Chemotherapy, 56, 6054-6
Currently, therapy of black-grain mycetoma caused by Madurella mycetomatis consists of extensive debridement of the infected tissue combined with prolonged antifungal therapy with ketoconazole or itraconazole. In the present study, the in vitro activ
Publikováno v:
Antimicrobial agents and chemotherapy. 38(1)
A direct study evaluating whether differential drug uptake of topical 2% miconazole and 2% ketoconazole from cream formulations into human stratum corneum correlated with differential pharmacological activity against Candida albicans was investigated
Autor:
Alan Forrest, Rachel L. Soon, Anima Poudyal, Phillip J. Bergen, Jovan Jacob, Brian T. Tsuji, Jürgen B. Bulitta, Zakuan Zainy Deris, David L. Paterson, Heidi H. Yu, Jian Li, Roger L. Nation, Kathryn Erin Davis, Tony Velkov, Caron K. Ku
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:5103-5112
Multidrug-resistant (MDR) Klebsiella pneumoniae may require combination therapy. We systematically investigated bacterial killing with colistin and doripenem mono- and combination therapy against MDR K. pneumoniae and emergence of colistin resistance
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:4569-4574
Telaprevir is a hepatitis C virus protease inhibitor that is both a substrate and an inhibitor of CYP3A. Amlodipine and atorvastatin are both substrates of CYP3A and are among the drugs most frequently used by patients with hepatitis C. This study wa
Autor:
Andreas Mårtensson, Zul Premji, Pedro Gil, Sabina Dahlström, Michael Ashton, Anna Färnert, Anna Annerberg, Anders Björkman, Billy Ngasala, Sofia Friberg Hietala, Niklas Lindegardh
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and