Zobrazeno 1 - 7
of 7
pro vyhledávání: '"11"'
Autor:
Guillem Prats, Beatriz Mirelis, M. Teresa Jimenez de Anta, Joaquim Ruiz, Ferran Sanchez, Jordi Vila, Ferran Navarro
Publikováno v:
Scopus-Elsevier
ResearcherID
Universitat Autònoma de Barcelona
ResearcherID
Universitat Autònoma de Barcelona
Haemophilus influenzae is a frequent cause of upper and lower respiratory tract infections (9). The new fluoroquinolones have been widely used as therapy for respiratory tract infections and have shown good activity against H. influenzae (3). Resista
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:3370-3380
We determined the target enzyme interactions of garenoxacin (BMS-284756, T-3811ME), a novel desfluoroquinolone, in Staphylococcus aureus by genetic and biochemical studies. We found garenoxacin to be four- to eightfold more active than ciprofloxacin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:1649-1653
Streptococcus pneumoniae is one of the most important pathogens and is responsible for community-acquired pneumonia, acute otitis media, and meningitis. Recently, the worldwide prevalence of penicillin-resistant S. pneumoniae has become a serious pro
Autor:
Todd A. Davies, Kensuke Nagai, Glenn A. Pankuch, Michael R. Jacobs, Peter C. Appelbaum, Bonifacio Dewasse
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:2740-2746
Ability of daily sequential subcultures in subinhibitory concentrations of clinafloxacin, ciprofloxacin, and trovafloxacin to select resistant mutants was studied in 10 pneumococci (ciprofloxacin MICs, 1 to 4 μg/ml, and clinafloxacin and trovafloxac
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:947-949
High-level quinolone resistance in Enterococcus faecium was associated with mutations in both gyrA and parC genes in 10 of 11 resistant strains. One low-level resistant strain without such mutations may instead possess an efflux mechanism or alterati
Publikováno v:
Antimicrobial agents and chemotherapy. 52(3)
Fluoroquinolone-resistant Burkholderia cepacia mutants were selected on ciprofloxacin. The rate of mutation in gyrA was estimated to be 9.6 × 10 −11 mutations per division. Mutations in gyrA conferred 12- to 64-fold increases in MIC, and an additi
Autor:
Shin-ichi Yoshida, Gopinath Balakrish Nair, Ken-ichiro Iida, Yoshiaki Kawamura, Takayuki Ezaki, Shanta Dutta
Publikováno v:
Antimicrobial agents and chemotherapy. 49(4)
After the emergence of multidrug-resistant Shigella strains (8, 11), fluoroquinolones, such as ciprofloxacin and norfloxacin, were used in India to treat shigellosis. However, recently, genetically clonal ciprofloxacin-resistant Shigella dysenteriae