Zobrazeno 1 - 10
of 31
pro vyhledávání: '"11"'
Autor:
S. Lalanne, Camille Tron, Florian Lemaitre, Eric Bellissant, Marie-Clémence Verdier, Antoine Petitcollin, S. Nimubona, C. Boglione-Kerrien
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (11), pp.e01166-17. ⟨10.1128/AAC.01166-17⟩
Antimicrobial Agents and Chemotherapy, 2017, 61 (11), pp.e01166-17. ⟨10.1128/AAC.01166-17⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (11), pp.e01166-17. ⟨10.1128/AAC.01166-17⟩
Antimicrobial Agents and Chemotherapy, 2017, 61 (11), pp.e01166-17. ⟨10.1128/AAC.01166-17⟩
Posaconazole is extensively used for prophylaxis for invasive fungal infections. The gastro-resistant tablet formulation has allowed the bioavailability issues encountered with the oral suspension to be overcome. However, overexposure is now frequent
Autor:
Phillip Hay, Sherene S. Min, Yu Lou, Marta Boffito, Graeme Moyle, Ivy Song, Chris Higgs, Elena M. Guerini, Carl Fletcher, Geoffrey J. Yuen
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:1532-1538
Abacavir (ABC) is administered either at 600 mg once daily (ABC 600 mg QD) or 300 mg twice daily (ABC 300 mg BID) in anti-human immunodeficiency virus (anti-HIV) combination therapy. Although ABC plasma pharmacokinetics following each regimen has bee
Autor:
Monidarin Chou, Julie Bertrand, Olivier Segeral, Céline Verstuyft, Laurence Borand, Emmanuelle Comets, Clotilde Le Tiec, Laurent Becquemont, Vara Ouk, France Mentre, Anne-Marie Taburet
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2010, 54 (10), pp.4432-9. ⟨10.1128/AAC.00512-10⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2010, 54 (10), pp.4432-9. ⟨10.1128/AAC.00512-10⟩
The aims of this ANRS12154 open-label, single-center, multiple-dose pharmacokinetic study were to characterize nevirapine pharmacokinetics in a Cambodian population of HIV-infected patients and to identify environmental and genetic factors of variabi
Autor:
Robert M. Grant, Kayla Campbell, Jose R Castillo-Mancilla, Lane R. Bushman, Sybil Hosek, Stacey S Coleman, Samantha MaWhinney, Craig M. Wilson, Edward M. Gardner, David V. Glidden, Sharon M Seifert, Peter L. Anderson, Jia-Hua Zheng, Kevin McAllister, Albert Y. Liu
Publikováno v:
Antimicrobial agents and chemotherapy, vol 60, iss 11
New objective measures of antiretroviral adherence are needed. We determined if emtricitabine triphosphate (FTC-TP) in dried blood spots (DBS) can be used as a marker of recent dosing with tenofovir disoproxil fumarate-emtricitabine (TDF-FTC). The ha
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:2078-2085
Isavuconazole is a novel broad-spectrum triazole antifungal agent. This open-label dose escalation study assessed the safety and pharmacokinetics of intravenous isavuconazole prophylaxis in patients with acute myeloid leukemia who had undergone chemo
Autor:
Nicholas A. Kartsonis, Johan Maertens, Oliver A. Cornely, Werner J. Heinz, Andrew J. Ullmann, Hetty Waskin, Michael N. Robertson, Hernando Patino, Maria Caceres, Gopal Krishna
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:3610-3617
This was a phase 1B, dose-ranging, multicenter, pharmacokinetics, and safety study of cyclodextrin-based posaconazole intravenous (i.v.) solution administered through a central line to subjects at high risk for invasive fungal disease (part 1 of a 2-
Publikováno v:
Antimicrobial Agents and Chemotherapy. 31:815-817
The objective of this study was to quantitate cefotaxime and its active metabolite, desacetyl cefotaxime, in the distal airways and to compare these levels to concentrations in plasma. Respiratory secretions were obtained from the subsegmental level
Autor:
John Tjia, Enmoore Lin, Akil Jackson, Marta Boffito, Andrew Hill, Marco Siccardi, Saye Khoo, Rebekah Puls, Victoria Watson, Alieu Amara, Paul Fahey, Laura Else, David Back, Sean Emery
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:1427-1433
There is interest in evaluating the efficacy of lower doses of certain antiretrovirals for clinical care. We determined here the bioequivalence of plasma lamivudine (3TC) and intracellular 3TC-triphosphate (3TC-TP) concentrations after the administra
Autor:
Saye Khoo, Alessandro Schipani, Giovanni Di Perri, Marco Simiele, Antonio D'Avolio, Howard L. McLeod, Gerry Davies, Charoen Chuchuttaworn, Sonia Rodríguez Novoa, Marco Siccardi, Janelle M. Hoskins, Vincent Soriano, Natpratou Saguenwong, Andrew Owen, David Back, Lorena Baietto, Anne M. Dvorak, Nitipatana Chierakul, Stefano Bonora, Lorena Cuenca
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:5242-5250
Atazanavir (ATV) plasma concentrations are influenced by CYP3A4 and ABCB1, which are regulated by the pregnane X receptor (PXR; NR1I2). PXR expression is correlated with CYP3A4 in liver in the absence of enzyme inducers. The PXR single nucleotide pol
Autor:
Patrick Mamoudy, Nicole Desplaces, Frédérick Durand, Valérie Zeller, Luc Lhotellier, Jean-Marc Ziza, Marie-Dominique Kitzis
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:883-887
Cefazolin has been used for many years to treat bone and joint infections. Because of its time-dependent antimicrobial activity, continuous infusion would potentially be beneficial. We report on the feasibility, safety, and efficacy of prolonged cont