Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jensen, A"'
Publikováno v:
Annals of the Rheumatic Diseases. 80:1064.1-1064
Background:Rheumatoid arthritis (RA) is a chronic, autoimmune disease characterized by inflammation of the synovium, cartilage and bone leading to joint swelling, tenderness, and dysfunction. The destruction of the joint tissue involves degradation o
Publikováno v:
Annals of the Rheumatic Diseases. 80:444.1-444
Background:Many systemic sclerosis (SSc) patients develop lung fibrosis, which contribute significantly to increased mortality1. Activated and proliferating fibroblasts are responsible for the excessive extracellular matrix (ECM) formation and stiffe
Autor:
Olga Ziouzina, J. Reis, Raj Carmona, Joel Paschke, Liam Martin, Walter P. Maksymowych, Ariel Masetto, Stephanie Keeling, S. Rohekar, Jon Chan, A. Carapellucci, R. Dadashova, Dianne Mosher, Robert G. W. Lambert, Ulrich Weber, Jensen Yeung, Sibel Zehra Aydin
Publikováno v:
Annals of the Rheumatic Diseases. 80:224.2-224
Background:Axial spondyloarthritis (axSpA) presents diagnostic challenges incurring a delay of up to a decade and relies considerably on radiographic and MRI evidence of sacroiliitis which has led to the development of classification criteria which a
Autor:
Asger Reinstrup Bihlet, M.A. Karsdal, A.-C. Bay-Jensen, F. Moreau, Hans Gühring, Jeppe Ragnar Andersen
Publikováno v:
Annals of the Rheumatic Diseases. 79:800-801
Background:In osteoarthritis (OA), response to different interventions could be more pronounced in different endotypes of cartilage turnover. Data from UK biobank suggest that an endotype of low cartilage repair is associated with structural progress
Autor:
J. Hagstrup Christensen, Dovile Sinkeviciute, M.A. Karsdal, S Holm Nielsen, E. Berg Schmidt, Søren Risom Kristensen, Annette Schlemmer, Anne-Christine Bay-Jensen
Publikováno v:
Annals of the Rheumatic Diseases. 79:1912-1913
Background:Psoriatic Arthritis (PsA) is a chronic inflammatory disease, characterized by involvement of skin, axial and peripheral skeleton. Prolargin is a class II small leucine-rich proteoglycan found to be expressed in connective tissues of patien
Autor:
N. Oparina, Malin C. Erlandsson, Gergely Katona, Anastasios E. Damdimopoulos, Maria Bokarewa, Karin M. E. Andersson, Maja Jensen, Maria-Jose Garcia-Bonete
Publikováno v:
Annals of the Rheumatic Diseases. 79:231.2-232
Background:The oncogenic protein survivin is a marker of severe rheumatoid arthritis (RA). High serum levels of Survivin predict progressive joint damage1and poor treatment response2.Objectives:To study the role of survivin in the transcriptional reg
Publikováno v:
Annals of the Rheumatic Diseases. 79:1094.2-1095
Background:Systemic sclerosis has vascular, inflammatory and fibrotic components, which may be associated with different growth factors and cytokines. Platelet derived growth factor (PDGF) is associated with the vasculature, whereas tumor necrosis fa
Autor:
Asger Reinstrup Bihlet, Hans Gühring, Christoph Ladel, Yunyun Luo, A. Manginelli, F. Moreau, M.A. Karsdal, Yi He, Jeppe Ragnar Andersen, A.-C. Bay-Jensen
Publikováno v:
Annals of the Rheumatic Diseases. 79:117.1-118
Background:It is challenging to monitor treatment effects after intra-articular (IA) injection with tissue modifying drugs. Assessment of biomarker levels in synovial fluid may be one solution to the challenge. Sprifermin is a truncated form of fibro
Autor:
Patrik Önnerfjord, M.A. Karsdal, Solveig Skovlund Groen, Christian S. Thudium, S Holm Nielsen, Dovile Sinkeviciute, A.-C. Bay-Jensen
Publikováno v:
Annals of the Rheumatic Diseases. 79:240-240
Background:Altered extracellular matrix (ECM) remodelling is an important part of the pathology seen in joint degenerative diseases. Type II collagen is the most abundant ECM protein in the cartilage and provides the tissue with essential tensile str
Autor:
Mukundan Attur, Svetlana Krasnokutsky, Inger Byrjalsen, S.B. Abramson, A.-C. Bay-Jensen, Tina Manon-Jensen, Morten Karsdal, J. Samuals
Publikováno v:
Annals of the Rheumatic Diseases. 75:829.2-829
Background Osteoarthritis (OA) is heterogeneous disease characterized by pain and tissue destruction which is in some case concomitant with inflammation. However, the link between pain and tissue destruction is yet unknown, and there is a lack object