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Autor:
Johan Rönnelid, Jana Tomasová Studýnková, Maryam Dastmalchi, Eva Lindroos, Patrick Gordon, Anna Tjärnlund, Helene Alexanderson, Ingrid E. Lundberg, Cecilia Wick, Quan Tang, Herman Mann, Rohit Aggarwal, Jiri Vencovsky, Rosaria Salerno, Radka Chura, Nicola J. Gullick
Publikováno v:
Annals of the Rheumatic Diseases. 77:55-62
ObjectivesTo study the effects of abatacept on disease activity and on muscle biopsy features of adult patients with dermatomyositis (DM) or polymyositis (PM).MethodsTwenty patients with DM (n=9) or PM (n=11) with refractory disease were enrolled in
Autor:
Kenneth C. Kalunian, William P Kennedy, Joan T. Merrill, Xiaohui Wei, John C. Davis, Romeo Maciuca, Jacqueline McBride, Michael J. Townsend
Publikováno v:
Annals of the Rheumatic Diseases. 75:196-202
Objectives To examine the safety and efficacy of rontalizumab, a humanised IgG1 anti-interferon α (anti-IFN-α) monoclonal antibody, in patients with moderate-to-severe systemic lupus erythematosus (SLE). Methods Patients with active SLE were random
Autor:
Philip J. Mease, Philip Robinson, Maxime Dougados, Zirke Wiid, Lisa Marshall, Paul Bird, Matthew A. Brown, Heather Jones, Filip Van den Bosch, Annette Szumski, Christine Surian
Publikováno v:
Annals of the rheumatic diseases. 77(7)
The efficacy of tumour necrosis factor alpha (TNFα) inhibitors for patients with non-radiographic axial spondyloarthritis (nr-axSpA) has now been firmly established1–3; however, identification of objective markers, predictive of treatment response
Autor:
Jonathan Boutemy, Zahir Amoura, Gaëlle Leroux, Daniel Wendling, Amadou Konaté, Pierre-Yves Jeandel, Camille Garnier, Fanny Andry, Arsène Mekinian, Alexis Mathian, Aurore Palmaro, Philippe Arlet, Jean-Baptiste Gaultier, Jean-Charles Piette, Benjamin Terrier, Pascal Cathébras, Sabine Berthier, Laurent Sailler, Laurent Arnaud, Nathalie Costedoat-Chalumeau, Patrice Cacoub, Grégory Pugnet, Guillaume Moulis, Maryse Lapeyre-Mestre, Elisabeth Solau-Gervais, Laurence Bouillet, Olivier Espitia
Publikováno v:
Annals of the Rheumatic Diseases. :annrheumdis-2017
Objectives To assess the efficacy and the safety of biologics in a cohort of patients with relapsing polychondritis (RP). Methods We conducted a French multicentre retrospective cohort study including patients treated with biologics for RP. Efficacy
Autor:
Peter Lamprecht, Thierry Schaeverbeke, Hendrik Schulze-Koops, Eugen Feist, Jürgen Rech, Bernhard Hellmich, Eduardo Schiffrin, Delphine S. Courvoisier, Jacques Morel, Thierry Martin, Eric Hachulla, Bruno Fautrel, Andrew Sleight, Cem Gabay, Ina Kötter, Mohamed Hamidou, François Spertini
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2018, 13, pp.annrheumdis--2017--212608. ⟨10.1136/annrheumdis-2017-212608⟩
Annals of the Rheumatic Diseases, Vol. 77, No 6 (2018) pp. 840-847
Annals of the Rheumatic Diseases, 2018, 13, pp.annrheumdis--2017--212608. ⟨10.1136/annrheumdis-2017-212608⟩
Annals of the rheumatic diseases, vol. 77, no. 6, pp. 840-847
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2018, 13, pp.annrheumdis--2017--212608. ⟨10.1136/annrheumdis-2017-212608⟩
Annals of the Rheumatic Diseases, Vol. 77, No 6 (2018) pp. 840-847
Annals of the Rheumatic Diseases, 2018, 13, pp.annrheumdis--2017--212608. ⟨10.1136/annrheumdis-2017-212608⟩
Annals of the rheumatic diseases, vol. 77, no. 6, pp. 840-847
Objectives Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disease; its management is largely empirical. This is the first clinical study to determine if interleukin (IL)-18 inhibition, using the recombinant human IL-18 bindi
Autor:
Joachim Sieper, Denis Poddubnyy, Johanna Callhoff, In-Ho Song, Joachim Listing, Martin Rudwaleit, Uta Syrbe, Kay-Geert A. Hermann, Jürgen Braun
Publikováno v:
Annals of the rheumatic diseases. 75(8)
Background To date, only a single controlled trial provided evidence that non-steroidal anti-inflammatory drugs (NSAIDs) given continuously reduce radiographic progression compared with an on-demand therapy over 2 years in patients with ankylosing sp
Autor:
Hana Ayoob, Judith McCaffrey, Andrea Zatkova, Christa van Kan, Carin Junestrand, Jonathan C. Jarvis, Andrew T. Hughes, Kim-Hanh Le Quan Sang, Helen Bygott, Gordon A. Ross, Lakshminarayan R. Ranganath, Richard Imrich, Anthony K Hall, Dinny Laan, Trevor Cox, Peter Christensen, Mattias Rudebeck, James A. Gallagher, Nicolas Sireau, Torbjörn Kullenberg, Lennart Svensson, Eftychia E. Psarelli, Birgitta Olsson, Daniela Braconi, Federica Genovese, Richard Fitzgerald, Oliver Timmis, Jozef Rovensky, Martina Nemethova, Anna M. Milan, Arvid Cronlund, Annalisa Santucci, Johan Szamosi, John Dutton, M. C. Briggs
Publikováno v:
Annals of the rheumatic diseases. 75(2)
Background Alkaptonuria (AKU) is a serious genetic disease characterised by premature spondyloarthropathy. Homogentisate-lowering therapy is being investigated for AKU. Nitisinone decreases homogentisic acid (HGA) in AKU but the dose-response relatio