Zobrazeno 1 - 10
of 102
pro vyhledávání: ''
Publikováno v:
Annals of the New York Academy of Sciences. 1148:154-160
Vasopressin (AVP) deficient homozygous Brattleboro rats exhibit severe osmotic challenges due to waterless chronic hypernatremia and hyperosmolality. We investigated the effect of xylazine, an alpha2-adrenoceptor agonist, on the activity of oxytocine
Autor:
Livia Pasquali, Gloria Lazzeri, Antonio Paparelli, Francesco Fornai, Ciro Isidoro, Stefano Ruggieri
Publikováno v:
Annals of the New York Academy of Sciences. 1139:191-196
Methamphetamine causes nigrostriatal denervation and striatal dopamine loss, while sparing nigral cell bodies. Nigral dopamine neurons feature autophagic vacuoles and cytoplasmic alpha-synuclein-, ubiquitin- and parkin-positive inclusion-like bodies.
Autor:
Frederico C. Pereira, Teresa Morgadinho, Vera M. Mendes, Syed F. Ali, Elsa Marques, Carlos Fontes Ribeiro, Tice Macedo, Marta R. Rolo
Publikováno v:
Annals of the New York Academy of Sciences. 1139:212-221
The glutamate-glutamine cycle between neurons and glia is tightly related to excitatory glutamatergic and inhibitory GABAergic regulation in brain. The role of this neuron-astrocyte cross-talk on the neurotoxicity induced by amphetamines is not under
Autor:
Hari Shanker Sharma, Syed F. Ali
Publikováno v:
Annals of the New York Academy of Sciences. 1139:242-258
The psychostimulant 3,4-,ethylenedioxymethamphetamine (MDMA, "ecstasy") is known to induce hyperthermia and alterations in neurochemical metabolism in the CNS. However, the detailed cellular or molecular mechanisms behind MDMA-induced neurotoxicity a
Autor:
Alessandra Tiziana Peana, Miriam Melis, Paolo Enrico, Alessandra Lintas, Marco Diana, Donatella Sirca
Publikováno v:
Annals of the New York Academy of Sciences. 1139:307-317
Ethyl alcohol (EtOH), the main psychoactive ingredient of alcoholic drinks, is widely considered responsible for alcohol abuse and alcoholism through its positive motivational properties, which depend, at least partially, on the activation of the mes
Autor:
Frank C. Barone, Giora Z. Feuerstein, Juan L. Gu, Robert R. Ruffolo, Paul G. Lysko, Tian L. Yue
Publikováno v:
Annals of the New York Academy of Sciences. 738:230-242
The antioxidant activities of carvedilol have been demonstrated in a wide variety of test systems, including (i) physicochemical (EPR studies), (ii) biochemical (measurement of lipid peroxidation and endogenous antioxidant depletion), (iii) cellular,
Persistent and Reversible Morphine Withdrawal-Induced Morphological Changes in the Nucleus Accumbens
Publikováno v:
Annals of the New York Academy of Sciences. 1074:446-457
Morphine withdrawal produces a hypofunction of mesencephalic dopamine (DA) neurons which impinge upon medium spiny neurons (MSN) of the forebrain. After chronic treatment rats were either spontaneously or pharmacologically withdrawn from chronic morp
Autor:
Antonio Paparelli, Paola Lenzi, Paola Soldani, Francesco Fornai, G Mauceli, Carla I. Busceti, Antonio Pellegrini
Publikováno v:
Annals of the New York Academy of Sciences. 1074:191-197
alpha-Synuclein is a presynaptic protein involved in various degenerative disorders now defined as synucleinopathies. These include neurological diseases that share a few pathological features consisting of aggregates of both normal and altered alpha
Autor:
Alessia Natoli, Walter Adriani, Elsa Traina, Emma Di Consiglio, Emanuela Testai, Damiana Leo, Giovanna De Angelis, Giovanni Laviola, Carla Perrone-Capano, Maria Guarino
Publikováno v:
Annals of the New York Academy of Sciences. 1074:52-73
Exposure to methylphenidate (MPH) during adolescence is the elective therapy for attention deficit/hyperactivity disorder (ADHD) children, but raises major concerns for public health, due to possibly persistent neurobehavioral changes. Rats (30- to 4
Publikováno v:
Annals of the New York Academy of Sciences. 939:179-186
Nefiracetam is a new pyrrolidone nootropic drug that is being developed for clinical use in the treatment of post-stroke vascular-type and Alzheimer's-type dementia. Among a few neuroreceptors that have been identified as potential targets of nootrop