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Autor:
Alessandra Tiziana Peana, Miriam Melis, Paolo Enrico, Alessandra Lintas, Marco Diana, Donatella Sirca
Publikováno v:
Annals of the New York Academy of Sciences. 1139:307-317
Ethyl alcohol (EtOH), the main psychoactive ingredient of alcoholic drinks, is widely considered responsible for alcohol abuse and alcoholism through its positive motivational properties, which depend, at least partially, on the activation of the mes
Publikováno v:
Annals of the New York Academy of Sciences. 1074:178-190
The human immunodeficiency virus-1 (HIV-1) affects the central nervous system (CNS) in approximately 30% of infected individuals and basal ganglia structures seem to be most affected. The HIV-1-transactivating protein, Tat, has been suggested to be p
Spinal Cord Neuroplasticity following Repeated Opioid Exposure and Its Relation to Pathological Pain
Autor:
David J. Mayer, Jianren Mao
Publikováno v:
Annals of the New York Academy of Sciences. 933:175-184
Convincing evidence has accumulated that indicates neuroplastic changes within the spinal cord in response to repeated exposure to opioids. Such neuroplastic changes occur at both cellular and intracellular levels. It has been generally acknowledged
Autor:
L. J. Almodóvar-Fábregas, Carlos A. Jiménez-Rivera, J. T. Williams, E. Vázquez, N. Colon, C. A. Mejías-Aponte, R. Vazquez, R. Abreu, M. Mercado, O. Segarra, J. G. Dones
Publikováno v:
Annals of the New York Academy of Sciences. 965:157-171
The repeated use of psychostimulants in humans has been associated with progressive enhancement of anxiety, panic attacks, and eventually paranoid psychosis. The appearance of such behaviors has been termed behavioral sensitization, which forms part
Autor:
J. Amiel Rosenkranz, Anthony A. Grace
Publikováno v:
Annals of the New York Academy of Sciences. 985:488-491
Publikováno v:
Annals of the New York Academy of Sciences. 914:311-315
Methamphetamine (MAP) can reinforce intracranial self-stimulation (ICSS) in rats, that is, reward-seeking behavior. However, the ICSS can be inhibited by the stereotyped behavior induced by MAP. This study was designed to observe the mutual informati
Publikováno v:
Annals of the New York Academy of Sciences. 914:316-322
Mesolimbic dopamine neurons in the ventral tegmental area (VTA), which project to the nucleus accumbens and prefrontal cortex, play an important role in the regulation of emotion, rewarding, and cognition. The dopamine neurons in the VTA have also be
Autor:
G. Vankin, E. Shevtzova, Gregory F. Oxenkrug, A. Afanasiev, S. Bachurin, T. Serkova, N. Lermontova, B. Beznosko, T. Mukhina
Publikováno v:
Annals of the New York Academy of Sciences. 890:155-166
After a single injection of cholinergic neurotoxin ethylcholine aziridinium (AF64A, 3 nmol intracerebroventricularly (i.c.v.)), rats failed to perform the tasks in the active avoidance (learning and retention paradigms) and water maze tests. N-Acetyl
Autor:
James E. Zadina, Gordon A. Barr
Publikováno v:
Annals of the New York Academy of Sciences. 897:145-153
Endomorphin-1 and endomorphin-2 are recently described peptides with high affinity and specificity for the mu opioid receptor. They are believed to be the endogenous ligands for that receptor. We describe the maturation of the endomorphins in brain a
Autor:
T. Celeste Napier, Igor Mitrovic
Publikováno v:
Annals of the New York Academy of Sciences. 877:176-201
While the ventral pallidum (VP) is known to be important in relaying information between the nucleus accumbens and target structures, it has become clear that substantial information processing occurs within the VP. We evaluated the possibility that