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Publikováno v:
Annals of the New York Academy of Sciences. 1160:250-255
The hypothalamus plays a key role in the regulation of energy homeostasis and endocrine function. Relaxin-3 is a hypothalamic neuropeptide that belongs to the insulin superfamily of peptides. It is expressed in the nucleus incertus of the brainstem,
Publikováno v:
Annals of the New York Academy of Sciences. 1148:154-160
Vasopressin (AVP) deficient homozygous Brattleboro rats exhibit severe osmotic challenges due to waterless chronic hypernatremia and hyperosmolality. We investigated the effect of xylazine, an alpha2-adrenoceptor agonist, on the activity of oxytocine
Autor:
V. Z. C. Ye, K. A. Duggan
Publikováno v:
Annals of the New York Academy of Sciences. 805:713-716
In patients with congestive cardiac failure, treatment with ACE inhibitors results in peripheral vasodilatation and an increase in cardiac output without an increase in heart rate, which suggests a positive inotropic effect. This cannot be explained
Autor:
Abdu Adem, Irwin S. Chandranath, Sheela Benedict, Mohamed A. Fahim, Enyioma N. Obineche, Ernest Adeghate
Publikováno v:
Annals of the New York Academy of Sciences. 1084:223-234
Diabetes mellitus (DM) shows a markedly increased incidence of cardiovascular pathology that leads to hypertension, endothelial macro- and microangiopathy, diabetic nephropathy, and myocardial infarction. Atrial natriuretic peptide (ANP), is a 28 ami
Autor:
Shinji Muroya, Toshihiko Yada, Yoshimi Shimoda, Hirokazu Ohtaki, Toshiko Hori, Seiji Shioda, Shigeaki Uramura, Hisayuki Funahashi, Shigeo Nakajo
Publikováno v:
Annals of the New York Academy of Sciences. 921:211-217
Medullary neurons containing pituitary adenylate cyclase-activating polypeptide (PACAP) and noradrenalin (NA) project to the hypothalamus and they are involved in the regulation of arginine vasopressin (AVP) neurons. At the ultrastructural level, PAC
Publikováno v:
Scopus-Elsevier
The gaseous neuromodulator carbon monoxide has been shown to reduce the stimulated release of stress neuropeptides, such as vasopressin and oxytocin, from the rat hypothalamus in vitro, while evidence concerning corticotropin-releasing hormone is con
Publikováno v:
Annals of the New York Academy of Sciences. 1041:481-485
A reduction in the incidence and severity of rheumatoid arthritis is seen in pregnant women. Relaxin, a hormone of pregnancy, has been implicated in decreased immune responsiveness. Consequently, the effects of relaxin and estradiol valerate, alone o
Publikováno v:
Annals of the New York Academy of Sciences. 1025:612-618
Epidermal growth factor (EGF) and its structurally related proteins are involved in the developmental regulation of various brain neurons, including midbrain dopaminergic neurons. We recently reported EGF and EGF-receptor abnormalities in both the br
Publikováno v:
Annals of the New York Academy of Sciences. 1024:9-23
Death from anthrax has been reported to occur from systemic shock. The lethal toxin (LeTx) is the major effector of anthrax mortality. Although the mechanism of entry of this toxin into cells is well understood, its actions once inside the cell are n
Autor:
György M. Nagy, Boris Mravec, L. Kubovcakova, Marton Fekete, Ibolya Bodnár, Richard Kvetnansky
Publikováno v:
Annals of the New York Academy of Sciences. 1018:124-130
Catecholamines (CAs) are significantly involved in the regulation of homeostasis of the organism at rest and especially during stressful situations. Stress induces increases in plasma CA (epinephrine and norepinephrine) levels and prolactin (PRL) rel