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Publikováno v:
Annals of the New York Academy of Sciences. 856:53-61
There is now good evidence that vasopressin (AVP) acts, in the male rat, as a neurotransmitter in the ventral septal area to reduce fever. In light of the well known sexual dimorphism in the AVP innervation of the brain, we asked if female rats would
Autor:
Georges Pelletier
Publikováno v:
Annals of the New York Academy of Sciences. 680:246-259
The major sites of POMC gene expression are the intermediate and anterior lobes of the pituitary and the arcuate nucleus of the hypothalamus. We have investigated the regulation of POMC mRNA levels in the pituitary and hypothalamus by quantitative in
Autor:
Marianne Halberg Larsen, Alexander Kiss, Jens D. Mikkelsen, Henrik H. Hansen, Jana Bundzikova
Publikováno v:
Annals of the New York Academy of Sciences. 1148
The control of the corticotropin-releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) is balanced by excitatory and inhibitory inputs. The GABA-A receptor, which is a major target for the inhibitory control, is composed o
Publikováno v:
Annals of the New York Academy of Sciences. 997
The central nervous system (CNS) is one of the main target tissues for sex steroid hormones, which act both through genomic mechanisms, modulating synthesis, release, and metabolism of many neuropeptides and neurotransmitters, and through nongenomic
Autor:
Froylan Vargas, Olivier Frerot, Christiane Rose, Katherine A. Zuzel, Jean-Charles Schwartz, Mi Dam Trung Tuong
Publikováno v:
Annals of the New York Academy of Sciences. 448
An apparently novel sulfotransferase present in microsomal and vesicular fractions from rat brain is able to transfer [35S]sulfate groups from [35S]PAPS to CCK derivatives. Its optimum pH (approximately 6), its substrate specificity, and its subcellu