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Publikováno v:
Annals of Otology, Rhinology & Laryngology. 126:573-580
Objectives: Regulated on activation normal T cell expressed and secreted (RANTES) and eotaxin-2 have been postulated to be responsible for eosinophilia in chronically inflamed nasal mucosa. This study evaluated mucosal production of RANTES and eotaxi
Publikováno v:
The Annals of otology, rhinology, and laryngology, vol 124, iss 7
Objective: Corticosteroids may be beneficial in treating vocal fold scarring. Current drug delivery methods do not permit controlled corticosteroid release. Here we investigate the effects of poly-lactic-co-glycolic acid (PLGA) microparticles loaded
Autor:
David A. Kieff, Nicolas Y. Busaba
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 114:941-945
Objectives: Twenty-four consecutive patients with symptomatic nasal polyposis and nonallergic or perennial rhinitis who were undergoing chronic nasal steroid therapy were prospectively evaluated for response to adjunctive oral montelukast sodium ther
Autor:
Tetsuo Himi, Shin-ichirou Narita, Etsuko Kanaizumi, Hideaki Shirasaki, Kazumasa Watanabe, Nobuhiro Konno, Jun Sato
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 113:941-945
To evaluate the effect of cetirizine hydrochloride on substance P release in allergic rhinitis, we performed a single-blind placebo-controlled study of 14 patients with perennial allergic rhinitis (7 treated with cetirizine and 7 with placebo). After
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 113:465-473
Glucocorticoids are known to be effective in the treatment of nasal polyps (NPs). To examine the mechanisms of their effect, we evaluated 1) the ability of glucocorticoids to induce the apoptosis of eosinophils and T lymphocytes in NPs, and 2) the ab
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 109:641-645
This study was conducted to evaluate the effectiveness of angiogenesis inhibitor 6- O-( N-chloroacetyl-carbamoyl)-fumagillol (TNP-470, AGM-1470) in the treatment of nasopharyngeal carcinoma (NPC) alone and in combination with cytotoxic agents. Forty-
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 108:554-558
The effect of an antiallergic drug on the evacuation of middle ear effusion (MEE) from the tubotympanum was investigated by means of an animal model with both otitis media with effusion (OME) and allergic rhinitis. Azelastine hydrochloride (AZ), an o
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 102:537-542
Time course studies of electrocochleography and the auditory brain stem response were performed in guinea pigs that were passively sensitized by sera containing antidinitrophenyl reaginic antibody and specifically challenged by dinitrophenyl—bovine
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 101:16-20
The mechanism of clinical effectiveness of low-dose and long-term erythromycin (EM) treatment for diffuse panbronchiolitis, sinobronchial syndrome, and associated otitis media with effusion was investigated by studying the effects of EM on tumor necr
Autor:
Anil K. Lalwani, Nancy L. Snyderman
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 100:484-487
Cytomegalovirus (CMV) infections in patients with acquired immunodeficiency syndrome are common and may present as retinitis, encephalitis, esophagitis, gastritis, enterocolitis, adrenalitis, or pneumonitis. Three patients are presented with pharynge