Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Theodore R. Holman"'
Autor:
Victor M. Darley-Usmar, Giovanni Coppola, Domenico Praticò, Rajiv R. Ratan, Lauren Alin, Cassandra M. Wilkinson, Megan W. Bourassa, Stephanie C. Sanchez, David Brand, Amit Kumar, Frederick Colbourne, Theodore R. Holman, S. Thomas Carmichael, Saravanan S. Karuppagounder, Ginger L. Milne, Colby A. Nadeau, Yingxin Chen, John T. Pinto, Kristen Dietrich, Steve Perry
Publikováno v:
Annals of Neurology. 84:854-872
Author(s): Karuppagounder, Saravanan S; Alin, Lauren; Chen, Yingxin; Brand, David; Bourassa, Megan W; Dietrich, Kristen; Wilkinson, Cassandra M; Nadeau, Colby A; Kumar, Amit; Perry, Steve; Pinto, John T; Darley-Usmar, Victor; Sanchez, Stephanie; Miln
N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E
Autor:
Saravanan S, Karuppagounder, Lauren, Alin, Yingxin, Chen, David, Brand, Megan W, Bourassa, Kristen, Dietrich, Cassandra M, Wilkinson, Colby A, Nadeau, Amit, Kumar, Steve, Perry, John T, Pinto, Victor, Darley-Usmar, Stephanie, Sanchez, Ginger L, Milne, Domenico, Pratico, Theodore R, Holman, S Thomas, Carmichael, Giovanni, Coppola, Frederick, Colbourne, Rajiv R, Ratan
Publikováno v:
Annals of Neurology
Objectives N‐acetylcysteine (NAC) is a clinically approved thiol‐containing redox modulatory compound currently in trials for many neurological and psychiatric disorders. Although generically labeled as an “antioxidant,” poor understanding of
Autor:
Klaus van Leyen, Eng H. Lo, Anton Pekcec, Joseph L. Witztum, Hulya Karatas, Theodore R. Holman, Rajiv R. Ratan, Stefanie Pallast, N. A. Smirnova, Netra Joshi, Kazim Yigitkanli, Irina G. Gazaryan, Emiri T. Mandeville, Joan Montaner
Publikováno v:
Annals of Neurology. 73:129-135
Targeting newly identified damage pathways in the ischemic brain can help to circumvent the currently severe limitations of acute stroke therapy. Here we show that the activity of 12/15-lipoxygenase was increased in the ischemic mouse brain, and 12/1