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Autor:
Peter E. Wu, Derek Leong
Publikováno v:
Annals of Internal Medicine. 172:509
Publikováno v:
Annals of Internal Medicine. 165:194
In November 2013, the U.S. Preventive Services Task Force issued a guideline on medications for risk reduction of primary breast cancer in women. Although mammography can detect early cases, it cannot prevent development of breast cancer. Tamoxifen a
Autor:
Michael H. Rosove, Wayne W. Grody
Publikováno v:
Annals of internal medicine. 151(4)
The U.S. Food and Drug Administration modified warfarin labeling in 2007 to suggest, but not mandate, pharmacogenetic testing. Genetic analysis is now commercially available. However, results predict only one third of all dosing variation, the value
Publikováno v:
Annals of internal medicine. 138(9)
Site-specific validation of the activated partial thromboplastin time (aPTT) therapeutic range is required to ensure administration of the optimal dose of unfractionated heparin. Therapeutic ranges of 1.5 to 2.5 times the control value are subtherape
Autor:
Gary Peters, Clifford W. Colwell, Anne K. Webster, Paul A. Lotke, Bruce L. Davidson, Jeffrey S. Ginsberg, Charles W. Francis, Scott D. Berkowitz, Jay R. Lieberman, James Whipple
Publikováno v:
Annals of internal medicine. 137(8)
Background Warfarin is used for prophylaxis of venous thromboembolism in patients undergoing total knee arthroplasty. However, it is associated with rates of deep venous thrombosis (DVT) of approximately 38% to 55% and requires routine coagulation mo
Autor:
Bruno Falissard, Kamran Samii, Patrice Nordmann, Fabrice Parker, Amal Karim, Alain Mercat, Olivier Mimoz, Christian Richard, Marie Cosseron
Publikováno v:
Annals of internal medicine. 131(11)
Background Chlorhexidine is better than povidone-iodine for care of catheter sites, but it is not known whether chlorhexidine is superior in reducing blood culture contamination. Objective To determine whether alcoholic chlorhexidine is a more effect
Autor:
Axel von Herbay, Thomas Marth, Warren Strober, Thomas Schneider, Andreas Stallmach, Martin Zeitz
Publikováno v:
Annals of internal medicine. 129(11)
Autor:
Thomas L. Ortel, Stephan Moll
Publikováno v:
Annals of internal medicine. 127(3)
Recommended therapeutic international normalized ratios (INRs) for oral anticoagulation in patients with lupus anticoagulants who sustain a thromboembolic event are controversial. Patients with lupus anticoagulants often have a prolonged prothrombin
Autor:
Elaine M. Hylek, Daniel E. Singer
Publikováno v:
Annals of internal medicine. 120(11)
To explore the rational use of anticoagulants, especially among the elderly, balancing antithrombotic efficacy and risk for hemorrhage. Previous prospective studies have not provided powerful assessments of risk factors for intracranial hemorrhage, t
Publikováno v:
Annals of internal medicine. 120(7)
To enhance understanding of the reliability of the international normalized ratio (INR) for monitoring warfarin therapy and its relation to other monitoring techniques.Prospective cohort study.A university hospital.79 patients attending an anticoagul