Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Todd L. Edwards"'
Autor:
Digna R. Velez Edwards, Shirley B. Russell, Todd L. Edwards, Scott M. Williams, Jacklyn N. Hellwege
Publikováno v:
Annals of Human Genetics. 82:206-215
Keloids are benign dermal tumors occurring approximately 20 times more often in individuals of African descent as compared to individuals of European descent. While most keloids occur sporadically, a genetic predisposition is supported by both famili
Autor:
Yu-Tang Gao, Wei Zheng, Nuri Kodaman, Todd L. Edwards, Robert Goodloe, Daniel Shriner, Scott M. Williams, Christopher I. Amos, Rafal S. Sobota
Publikováno v:
Annals of Human Genetics. 79:136-147
Summary The number of effectively independent tests performed in genome-wide association studies (GWAS) varies by population, making a universal P-value threshold inappropriate. We estimated the number of independent SNPs in Phase 3 HapMap samples by
Autor:
Yong-Bing Xiang, Xiao-Ou Shu, Honglan Li, Raquel Villegas, Todd L. Edwards, Yu-Tang Gao, Jirong Long, Qiuyin Cai, Hui Cai, Scott M. Williams, Wei Zheng, Tom A. Elasy
Publikováno v:
Annals of Human Genetics. 75:621-629
Type 2 diabetes (T2D) is a complex disease that results from the contribution of many genes (1) and environmental factors (2), as well as interactions among genes and the environment. Among the known factors that increase risk are high BMI (3–7) an
Autor:
Amber Burt, Liyong Wang, Stephan Züchner, William K. Scott, Todd L. Edwards, Jeffery M. Vance, Eden R. Martin, Megan W. Butler
Publikováno v:
Annals of Human Genetics. 75:201-210
Vitamin D and vitamin D receptor (VDR) have been postulated as environmental and genetic factors in neurodegeneration disorders including multiple sclerosis (MS), Alzheimer disease (AD), and recently Parkinson disease (PD). Given the sparse data on P
Autor:
Liyong Wang, William K. Scott, Burton L. Scott, Eden R. Martin, Margaret A. Pericak-Vance, Fatta B. Nahab, Stephan Züchner, Ioanna Konidari, Eric Powell, Cherylyn Almonte, Jonathan L. Haines, Todd L. Edwards, Gary W. Beecham, Amber Burt, Carlos Singer, Gaofeng Wang, Jeffery M. Vance, Jeffrey M. Stajich
Publikováno v:
Annals of Human Genetics. 74:97-109
Parkinson disease (PD) is a chronic neurodegenerative disorder with a cumulative prevalence of greater than one per thousand. To date three independent genome-wide association studies (GWAS) have investigated the genetic susceptibility to PD. These s
Autor:
Rafal S, Sobota, Daniel, Shriner, Nuri, Kodaman, Robert, Goodloe, Wei, Zheng, Yu-Tang, Gao, Todd L, Edwards, Christopher I, Amos, Scott M, Williams
Publikováno v:
Annals of human genetics. 79(2)
The number of effectively independent tests performed in genome-wide association studies and the corresponding genome-wide significance level varies by population. Therefore, a common p-value threshold may be inappropriate. To assess this, we estimat