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Publikováno v:
Anesthesiology
The prevention of perioperative neurocognitive disorders is a priority for patients, families, clinicians, and researchers. Given the multiple risk factors present throughout the perioperative period, a multicomponent preventative approach may be mos
Autor:
James E. Baumgardner, Thomas Hachenberg, Anders Larsson, Moritz Kretzschmar, Göran Hedenstierna, Thomas F. Schilling, Alf Kozian
Publikováno v:
Anesthesiology. 135:1042-1054
Background Kinetics of the uptake of inhaled anesthetics have been well studied, but the kinetics of elimination might be of more practical importance. The objective of the authors’ study was to assess the effect of the overall ventilation/perfusio
Autor:
Moritz Kretzschmar, Anders Larsson, James E. Baumgardner, Göran Hedenstierna, Thomas Hachenberg, Alf Kozian, Thomas F. Schilling
Publikováno v:
Anesthesiology. 135:1027-1041
Background Previous studies have established the role of various tissue compartments in the kinetics of inhaled anesthetic uptake and elimination. The role of normal lungs in inhaled anesthetic kinetics is less understood. In juvenile pigs with norma
Publikováno v:
Anesthesiology. 136:148-161
Background The relationship between late clinical outcomes after injury and early dynamic changes between fibrinolytic states is not fully understood. The authors hypothesized that temporal transitions in fibrinolysis states using rotational thromboe
Autor:
Sergey Karamnov, Timothy L. McMurry, Ju-Mei Ng, Randal S. Blank, Julianne Barlow, Hisashi Tsukada, Ritu R. Gill, Stephanie Yacoubian, Philip M. Hartigan, Jeffrey Swanson
Publikováno v:
Anesthesiology. 136:104-114
Background Central airway occlusion is a feared complication of general anesthesia in patients with mediastinal masses. Maintenance of spontaneous ventilation and avoiding neuromuscular blockade are recommended to reduce this risk. Physiologic argume
Autor:
Christian, Reiterer, Barbara, Kabon, Sven, Halvorson, Daniel I, Sessler, Edward J, Mascha, Andrea, Kurz, Alexander, Taschner
Publikováno v:
Anesthesiology. 136:127-137
Background Colloids are thought to sustain blood pressure and cardiac index better than crystalloids. However, the relative effects of intraoperative hydroxyethyl starch and crystalloid administration on the cardiac index and blood pressure remain un
Autor:
Kasun Wickramarachchi, Nicole Sheridan, Simon Yates, Scott McAlister, Forbes McGain, Brandon Chan
Publikováno v:
Anesthesiology. 135:976-991
Background Health care itself contributes to climate change. Anesthesia is a “carbon hotspot,” yet few data exist to compare anesthetic choices. The authors examined the carbon dioxide equivalent emissions associated with general anesthesia, spin
Autor:
Cheryl L. Maier, Roman M. Sniecinski
Publikováno v:
Anesthesiology
From preoperative medications to intraoperative needs to postoperative thromboprophylaxis, anticoagulants are encountered throughout the perioperative period. This review focuses on coagulation testing clinicians utilize to monitor the effects of the
Autor:
C. Philip Larson
Publikováno v:
Anesthesiology. 135:724-727
The Solubility of Halothane in Blood and Tissue Homogenates. By Larson CP, Eger EI, Severinghaus JW. Anesthesiology 1962; 23:349–55. Measured samples of human and bovine blood, human hemoglobin, and tissue homogenates from human fat and both human
Autor:
Elizabeth S. Jewell, Duan Li, Aleda Leis, Michael P. Puglia, Chelsea M. Kaplan, Megan Therrian, George A. Mashour, Minkyung Kim, UnCheol Lee, Phillip E. Vlisides
Publikováno v:
Anesthesiology. 135:813-828
Background Neurophysiologic complexity in the cortex has been shown to reflect changes in the level of consciousness in adults but remains incompletely understood in the developing brain. This study aimed to address changes in cortical complexity rel