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Autor:
Reine Ibala, Shubham Chamadia, Oluwaseun Akeju, Jennifer Mekonnen, Jason Z. Qu, Eunice Hahm, Juan C Pedemonte, Joseph J. Locascio, Jacob Gitlin, Katia M Colon, Breanna R Ethridge
Publikováno v:
Anesthesiology. 133:1021-1028
Background Ketamine is a dissociative anesthetic with analgesic properties. Ketamine’s analgesic properties have been suggested to result from its dissociative properties. To the authors’ knowledge, this postulate is unsubstantiated. The authors
Publikováno v:
Anesthesiology
BackgroundAnesthetics aim to prevent memory of unpleasant experiences. The amygdala and dorsal anterior cingulate cortex participate in forging emotional and valence-driven memory formation. It was hypothesized that this circuitry maintains its role
Publikováno v:
Anesthesiology. 125:1229-1241
A 77 year-old male is admitted to the hospital after sustaining a hip fracture. He has a past medical history of chronic obstructive pulmonary disease, hypertension, hyperlipidemia, chronic back pain, and hearing loss. Prior to surgery he receives mi
Publikováno v:
Anesthesiology, vol 131, iss 1
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Midazolam has been found to exacerbate or unmask limb motor dysfunction in patients with brain tumors. This study aimed to determine whethe
Autor:
Kathryn A. Salvati, Zhiyi Zuo, Howard P. Goodkin, Ryan Sica, Caroline Keller, Navya Atluri, Nadia Lunardi, Mark P. Beenhakker
Publikováno v:
Anesthesiology
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Previous studies suggest that rapid eye movement sleep rebound and disruption of rapid eye movement sleep architecture occur during the fir
Publikováno v:
Anesthesiology. 124:598-607
BackgroundSedation is commonly used in neurosurgical patients but has been reported to produce transient focal neurologic dysfunction. The authors hypothesized that in patients with frontal–parietal–temporal brain tumors, focal neurologic deficit
Autor:
Daqing Ma, Lingzhi Wu, Hailin Zhao, Cui Jiang, Charlotte L. Bevan, Guolin Wang, Robert D. Sanders, Tanweer Datoo, Akshay Date, Chunyan Wang
Publikováno v:
Anesthesiology. 129(5)
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Several factors within the perioperative period may influence postoperative metastatic spread. Dexmedetomidine and midazolam are widely use
Publikováno v:
Anesthesiology. 120:1354-1361
Background:Midazolam has been widely studied for preventing emergence agitation. The authors previously reported that in children with sevoflurane anesthesia, intravenous administration of midazolam (0.05 mg/kg) before the end of surgery reduced the
Autor:
Michel Struys, Hugo Vereecke, Peter M. Schumacher, Martin Luginbühl, Thomas Bouillon, Douglas J. Eleveld, Johannes H. Proost, Bjorn Heyse
Publikováno v:
Anesthesiology. 116:311-323
Background Various pharmacodynamic response surface models have been developed to quantitatively describe the relationship between two or more drug concentrations with their combined clinical effect. We examined the interaction of remifentanil and se
Publikováno v:
Anesthesiology. 113:429-437
Background Substantia gelatinosa of the spinal dorsal horn is crucial for transmission and modification of noxious stimuli. Previous studies have demonstrated that intrathecal midazolam, a benzodiazepine agonist, enhanced perioperative analgesia. Not