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Publikováno v:
Anesthesiology. 134:617-625
Background The median effective dose of ropivacaine required for producing an effective costoclavicular block has not yet been determined. The authors conducted this dose-finding study with the objective of determining the median effective dose of 0.
Autor:
Marco Gemma, Andrea Luigi Ambrosoli, Federico Bizzarri, G. Cappelleri, Giorgio Danelli, Valeria Cedrati
Publikováno v:
Anesthesiology. 129:241-248
What We Already Know about This Topic What This Article Tells Us That Is New Background Both extra- and intraneural sciatic injection resulted in significant axonal nerve damage. This study aimed to establish the minimum effective volume of intraneur
Publikováno v:
Anesthesiology. 122:1010-1020
Background: Even though ropivacaine is frequently used during orthopedic surgery, the relationship between plasma concentrations and degree of sensory anesthesia after a peripheral nerve block is currently unknown. The aim of this study was to charac
Autor:
Cyrus Motamed, Smail Hamouda, Emmanuelle Mouret-Fourme E, Pierre-Yves Dubois, Aline Albi-Feldzer, Christian Jayr, Ludivine Jouanneau
Publikováno v:
Anesthesiology. 118:318-326
Background:The efficacy of local anesthetic wound infiltration for the treatment of acute and chronic postoperative pain is controversial and there are no detailed studies. The primary objective of this study was to evaluate the influence of ropivaca
Publikováno v:
Anesthesiology. 125(3)
Rapid intravenous administration of lipid emulsion has become the standard treatment of severe local anesthetic systemic toxicity. This experiment in volunteers aimed at determining the effect of Intralipid® administration on the time to neurologic
Autor:
Olusegun K. Onibonoje, Michael C. Donohue, Loran Mounir-Soliman, Jennifer E. Stevens-Lapsley, Sherif Zaky, Leonard T. Buller, Daniel I. Sessler, Viktor E. Krebs, Chad Parrett, Lu Wang, Maria Bauer, Brian M. Ilfeld
Publikováno v:
Anesthesiology. 116:665-672
Background Whether decreasing the local anesthetic concentration during a continuous femoral nerve block results in less quadriceps weakness remains unknown. Methods Preoperatively, bilateral femoral perineural catheters were inserted in subjects und
Publikováno v:
Anesthesiology. 113:445-453
Background The potencies of bupivacaine and ropivacaine have been compared using up-and-down methodology, but their complete dose-response curves have not been compared. The authors performed a random allocation-graded dose-response study of epidural
Autor:
Paul J. Girard, Lisa K. Moeller, Scott T. Ball, Eliza J. Ferguson, Jennifer E. Stevens-Lapsley, Michael C. Donohue, Adam S. Fleisher, Brian M. Ilfeld, Vanessa J. Loland, Edward R. Mariano
Publikováno v:
Anesthesiology. 112:347-354
Background The main determinant of continuous peripheral nerve block effects--local anesthetic concentration and volume or simply total drug dose--remains unknown. Methods We compared two different concentrations and basal rates of ropivacaine--but a
Autor:
Serge Rohr, Pascal Gervaz, André Lienhart, Marc Beaussier, Jean-Xavier Mazoit, Yann Parc, Hanna El’Ayoubi, Jean-Jacques Eledjam, Louisa Azizi, Maxime Rollin, Celine Biermann, Eduardo Schiffer
Publikováno v:
Anesthesiology. 107:461-468
Background Blockade of parietal nociceptive afferents by the use of continuous wound infiltration with local anesthetics may be beneficial in a multimodal approach to postoperative pain management after major surgery. The role of continuous preperito
Autor:
Manoj K. Karmakar, Tony Gin, Bonita K. Law, April S. Y. Wong, Anthony M.-H. Ho, Steven L. Shafer
Publikováno v:
Anesthesiology. 103:704-711
Background Animal and volunteer studies indicate that ropivacaine is associated with less neurologic and cardiac toxicity than bupivacaine. Ropivacaine may offer advantages when used for thoracic paravertebral block. This study was designed to descri