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Publikováno v:
Anesthesiology. 103:126-129
Background In this randomized, double-blind study, the authors compared the effectiveness of a sequential epidural bolus (SEB) technique versus a standard continuous epidural infusion (CEI) technique of local anesthetic delivery. Both techniques used
Publikováno v:
Anesthesiology. 102:1205-1210
Background Epidural clonidine produces analgesia without motor impairment, and is associated with a local anesthetic-sparing effect during labor. The authors have recently demonstrated that epidural neostigmine initiates selective labor analgesia dev
Publikováno v:
Anesthesiology. 102:175-180
Background Major spine surgery with a dorsal or ventrodorsal approach causes severe postoperative pain. The use of continuous epidural analgesia through one or two epidural catheters placed intraoperatively by the surgeon has been shown to provide ef
Autor:
Satoshi Kurihara, Yasushi Mio, Norio Fukuda, Yasumasa Tanifuji, Yoshikiyo Amaki, Yoichiro Kusakari
Publikováno v:
Anesthesiology. 101:888-894
Background Recent evidence suggests that ropivacaine exerts markedly less cardiotoxicity compared with bupivacaine; however, the mechanisms are not fully understood at the molecular level. Methods Isolated ferret ventricular papillary muscles were mi
Autor:
F. Kayser Enneking, Timothy E. Morey, Brian M. Ilfeld, Lisa J. Thannikary, Robert A. Vander Griend
Publikováno v:
Anesthesiology. 101:970-977
Background This randomized, double-blind study investigated the efficacy of continuous and patient-controlled ropivacaine infusion via a popliteal sciatic perineural catheter in ambulatory patients undergoing moderately painful orthopedic surgery of
Autor:
Emmanuel Boselli, Bernard Allaouchiche, Dominique Chassard, Thomas Rimmelé, Richard Debon, Yann Cimino
Publikováno v:
Anesthesiology. 100:968-972
Background Although patient-controlled epidural analgesia (PCEA) during labor has been extensively studied in recent clinical trials, the role of a background infusion associated with self-administered boluses is still debated. The authors designed a
Publikováno v:
Anesthesiology. 100:973-978
Background The authors examined the hypothesis that epidural administration of local anesthetic, in contrast to epidural analgesia with morphine, inhibits postoperative protein oxidation during administration of glucose. Methods Fourteen patients wer
Publikováno v:
Anesthesiology. 100:922-925
Background Lower systemic toxicity reported with ropivacaine and levobupivacaine may produce less reliable recognition of inadvertent intravenous injection during regional anesthesia. This study was undertaken to determine whether ropivacaine and lev
Publikováno v:
Anesthesiology. 100:395-402
Background In this randomized, double-blind study, the authors investigated the efficacy of continuous and patient-controlled ropivacaine infusions via an infraclavicular perineural catheter in ambulatory patients undergoing moderately painful orthop
Autor:
Linda S. Polley, Cosmas van de Ven, Kathryn H. Goralski, Malachy O. Columb, Norah N. Naughton, Deborah S. Wagner
Publikováno v:
Anesthesiology. 99:1354-1358
Background The minimum local analgesic concentration has been defined as the median effective local analgesic concentration (EC50) in a 20-ml volume for epidural analgesia in the first stage of labor. The aim of this study was to assess the relative