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Autor:
G. Iohom, Brian D O'Donnell
Publikováno v:
Anesthesiology. 111:25-29
Background Ultrasound guidance facilitates precise needle and injectate placement, increasing axillary block success rates, reducing onset times, and permitting local anesthetic dose reduction. The minimum effective volume of local anesthetic in ultr
Publikováno v:
Anesthesiology. 107:305-311
Background: QX-314 is a quaternary lidocaine derivative considered to be devoid of clinically useful local anesthetic activity. However, several reports document that extracellular QX-314 application affects action potentials. Hence, the authors test
Publikováno v:
Anesthesiology. 97:1245-1249
Background Upper limb trauma occurs frequently in elderly patients for whom peripheral nerve blocks are often preferred for anesthesia. The characteristics of such regional blocks have, however, never been described in an elderly population. Therefor
Publikováno v:
Anesthesiology. 97:325-328
Background Levobupivacaine, a long acting, amino-amide, local anesthetic, may offer advantages over lidocaine for intravenous regional anesthesia (IVRA). The objective of this investigation was to compare levobupivacaine to lidocaine for IVRA. Method
Autor:
Joyce M. Hotz, Robert T. Wilder, Megumi Uezono, Joanne M. Curley, Jenny Castillo, Charles B. Berde, Joseph Tigner, Mark Chasin, Robert Langer
Publikováno v:
Anesthesiology. 85:1157-1166
Background Previous work showed that incorporation of dexamethasone (0.05 weight/weight percentage) into bupivacaine microspheres prolonged blockade by eight to 13 times compared with that produced by bupivacaine microspheres alone. The determinants
Publikováno v:
Anesthesiology. 78:155-162
BACKGROUND Midazolam is being selected increasingly for use in patients with cardiovascular compromise. Although clinical doses of midazolam have minimal effects on cardiac function, the influence of midazolam (and other benzodiazepine sedatives) on
Publikováno v:
Anesthesiology. 77:475-481
This study evaluates prolongation of spinal anesthesia by incorporating local anesthetics in lipid formulation. The duration and intensity of local anesthetic effect produced by different concentrations of procaine (1%, 2%, 4%), lidocaine (1%, 2%, 4%
Autor:
Markus Steinfath, A. Paris, Jens Scholz, Patrick Meybohm, Berthold Bein, Mike Ufer, Philipp-Alexander Brand, Florian Thiemann
Publikováno v:
Anesthesiology. 108(4)
Background Both propofol and volatile anesthetics have been reported to interact with the endocannabinoid system. The purpose of this study was to evaluate the effect of selective agonists for cannabinoid receptor types 1 and 2 on etomidate-induced s
Publikováno v:
Anesthesiology. 96(6)
Background The addition of small amounts of dexamethasone to extended-release formulations of bupivacaine in microcapsules has been found to prolong local analgesia in experimental studies, but no clinical data are available. Methods In a double-blin
Publikováno v:
Anesthesiology. 92(5)
Background The influence of spread of spinal anesthesia on the duration of spinal blockade has been suggested but never investigated specifically. Because elimination of local anesthetic from subarachnoid space is probably dependent of the surface av