Zobrazeno 1 - 10
of 10
pro vyhledávání: '"59"'
Autor:
Markus W. Hollmann, Ragnar Huhn, Coert J. Zuurbier, Wolfgang Schlack, Nina C. Weber, Benedikt Preckel, Kirsten M. Smeele, Andre Heinen
Publikováno v:
Anesthesiology. 109:830-836
Background The noble gas helium induces cardiac preconditioning. Whether activation of mitochondrial K(+) channels is involved in helium preconditioning (He-PC) is unknown. The authors investigated whether He-PC (1) is mediated by activation of Ca(2+
Autor:
Yugo Tagaito, Naohito Shimoyama, Hiroshi Nagase, Satoshi Toyama, Tsuyoshi Saitoh, Masashi Yanagisawa, Megumi Shimoyama
Publikováno v:
Anesthesiology. 128:992-1003
Background Sleepiness and decrease in attention are dose-limiting side effects of opioids. The orexin/hypocretin system plays an important role in maintaining wakefulness. This study aimed to explore the potential of a nonpeptide orexin receptor agon
Autor:
B Gallix, Boris Jung, S. Aufort, Stephanie Nougaret, Samir Jaber, Gregoire Mercier, Gerald Chanques, Moussa Cisse, Djillali Annane
Publikováno v:
Anesthesiology. 115:334-343
Background : Assessment and management of septic shock associated adrenal function remain controversial. The aim of this study was to explore the prognostic value of adrenal gland volume in adults with septic shock. Methods : A short cosyntropin test
Publikováno v:
Anesthesiology. 100:774-781
Background The authors determined the segmental effects of intracarotid verapamil in human subjects by using a novel method of measuring proximal and distal cerebrovascular resistance. Their hypothesis was that intracarotid verapamil, a calcium chann
Publikováno v:
Anesthesiology. 86:1104-1111
Background Ketamine is a potent bronchodilator that, in clinically used concentrations, relaxes airway smooth muscle in part by a direct effect. This study explored the role of calcium concentration (Ca2+) in this relaxation. Methods Canine trachea s
Autor:
Dennis T. Mangano, Paul Goehner, Brian O'Kelly, Jacqueline M. Leung, Nito Pineda, Brian A. Cason, Milton Hollenberg
Publikováno v:
Anesthesiology. 74:838-847
Whether isoflurane has the potential to produce coronary artery steal and associated myocardial ischemia is still controversial. Previous studies addressing this issue in humans did not purposefully control hemodynamics or use continuous measures of
Publikováno v:
Anesthesiology. 74(1)
Volatile anesthetics produce their negative inotropic effect on the heart mainly by interference with calcium homeostasis in the myocardial cell. In order to elucidate the mechanism of the depression, we have evaluated the effect of the volatile anes
Publikováno v:
Anesthesiology. 57:267-271
Recent clinical experience and previous experimental work indicate that propranolol may reverse sodium-nitroprusside-induced inhibition of hypoxic pulmonary vasoconstriction (HPV). Accordingly, the authors decided to test this possibility in an exper
Publikováno v:
Anesthesiology. 42(2)
The effects of halothane on the beating response of rat heart cells in tissue culture were studied using an optical-electronic monitoring device. A dose-response curve was obtained over a concentration range to as much as 5 vol per cent halothane. Th
Autor:
Mervyn Maze, Christopher M. Smith
Publikováno v:
Anesthesiology. 59(4)
The adrenergic receptor mechanism by which halothane sensitizes the myocardium to the ventricular arrhythmogenic properties of catecholamines is unknown. The new generation of selective adrenergic receptor antagonists have been used to determine whic