Zobrazeno 51 - 60
of 1 033
pro vyhledávání: ''
Publikováno v:
Anesthesiology. 102:35-40
Background The authors examined the notion that a reduction in succinylcholine dose from 1 mg/kg to approximately 0.6 mg/kg would allow a faster recovery of spontaneous ventilation and reduction in the incidence of hemoglobin desaturation during the
Autor:
Martin Luginbühl, Eleonora Zanderigo, Gorazd Sveticic, Andrea Gentilini, Valentina Sartori, Urs Eichenberger, Michele Curatolo
Publikováno v:
Anesthesiology. 101:1381-1393
Background The authors developed and applied a method to optimize the combination of bupivacaine, fentanyl, and clonidine for continuous postoperative lumbar epidural analgesia. Methods One hundred eighteen patients undergoing knee or hip surgery par
Autor:
Danette Daniel, Pamela Flood
Publikováno v:
Anesthesiology. 101:1417-1421
Background Despite pharmacological treatment, 70-80% of patients report moderate to severe pain after surgery. Because nicotine has been reported to have analgesic properties in animal and human volunteer studies, the authors assessed the analgesic e
Autor:
Uta Stegemann, Kristine Kellermann, Regina Hollweck, Monika Pape, Eberhard Kochs, Christian Werner, Eva Eberspächer, Kristin Engelhard, Peter Hutzler
Publikováno v:
Anesthesiology. 101:912-917
Background Propofol reduces neuronal damage from cerebral ischemia when investigated for less than 8 postischemic days. This study investigates the long-term effects of propofol on neuronal damage and apoptosis-related proteins after cerebral ischemi
Publikováno v:
Anesthesiology. 101:729-737
Background Oral transmucosal fentanyl citrate (OTF) was developed to provide rapid analgesia and is specifically approved for treating breakthrough cancer pain. Fentanyl in OTF is absorbed across the oral mucosa, but a considerable portion is swallow
Publikováno v:
Anesthesiology. 101:603-613
Background The currently available pharmacokinetic models for fentanyl were derived from normal weight patients and were not scaled to body weight. Their application to obese patients may cause overprediction of the plasma concentration of fentanyl.
Autor:
Ryan Hynd, Tim Meek, David M. Ryall, David W. Cooper, Rebekah Thompson, Manmohan S. Kokri, Leo Jeyaraj
Publikováno v:
Anesthesiology. 101:28-33
Background The authors have previously observed an apparent association between rostral spread of spinal anesthesia and choice of intravenous vasopressor given to maintain maternal systolic arterial pressure during cesarean delivery. This study teste
Autor:
John R. Lynch, David S. Warner, Maria Moldovan, Robert D. Pearlstein, Hazem Elsersy, Huaxin Sheng
Publikováno v:
Anesthesiology. 100:1160-1166
Background This study examined long-term outcome from severe forebrain ischemia in the rat, as a function of anesthetic given during the ischemic injury. Methods Rats were subjected to 10 min of near-complete forebrain ischemia while anesthetized wit
Autor:
John J. Savarese, Brenna Stein, Patel Sanjay Shashikant, Cynthia A. Lien, Eleanor Bradley, Matthew R. Belmont, Joseph Tjan
Publikováno v:
Anesthesiology. 100:768-773
Background An ultrashort-acting nondepolarizing neuromuscular blocking agent that could be an alternative to succinylcholine has been the focus of a concerted effort in the field of muscle relaxants. GW280430A showed a promising pharmacodynamic profi
Autor:
Andrew R. Wolf, Mark Schily, Peter A. Stoddart, Rob Eyres, Judith A. Nolan, Christopher M. Bolton, Frank Mazzeo, Jerrold Lerman
Publikováno v:
Anesthesiology. 99:1166-1174
Background Levobupivacaine, the levo-enantiomer of bupivacaine, is as potent as bupivacaine but less toxic. Therefore, the authors investigated the efficacy, safety, and pharmacokinetics of perioperative epidural levobupivacaine with and without fent