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Autor:
Danette Daniel, Pamela Flood
Publikováno v:
Anesthesiology. 101:1417-1421
Background Despite pharmacological treatment, 70-80% of patients report moderate to severe pain after surgery. Because nicotine has been reported to have analgesic properties in animal and human volunteer studies, the authors assessed the analgesic e
Autor:
John J. Savarese, Brenna Stein, Patel Sanjay Shashikant, Cynthia A. Lien, Eleanor Bradley, Matthew R. Belmont, Joseph Tjan
Publikováno v:
Anesthesiology. 100:768-773
Background An ultrashort-acting nondepolarizing neuromuscular blocking agent that could be an alternative to succinylcholine has been the focus of a concerted effort in the field of muscle relaxants. GW280430A showed a promising pharmacodynamic profi
Autor:
Hitoshi Furuya, Katsuyasu Kitaguchi, Takanori Sakamoto, Satoki Inoue, Masahiko Kawaguchi, Toshisuke Sakaki
Publikováno v:
Anesthesiology. 97:116-123
Background Since the time available to provide the cooling and rewarming is limited during deliberate mild hypothermia, the technique to accelerate the cooling and rewarming rate of core temperature has been studied. Amrinone has been reported to acc
Publikováno v:
Anesthesiology. 93:959-963
Background Conventional supine emergence in patients undergoing prone lumbar surgery frequently results in tachycardia, hypertension, coughing, and loss of monitoring as the patient is rolled supine. The prone position might facilitate a smoother eme
Autor:
Takahisa Goto, Katsuo Terui, Hayato Saito, Yoshiki Ishiguro, Yoshinori Nakata, Yoshihiko Tsuruta, Shigeho Morita, Yoshinari Niimi, Hiromasa Kawakami
Publikováno v:
Anesthesiology. 92:1043-1048
Background Although anesthesia with xenon has been supplemented with fentanyl, its requirement has not been established. This study was conducted to determine the plasma concentrations of fentanyl necessary to suppress somatic and hemodynamic respons
Publikováno v:
Anesthesiology. 89:894-906
Background Sufficient propofol or fentanyl doses necessary to prevent the response to skin incision do not necessarily attenuate hemodynamic responses during surgery. The goal of this study was to characterize the pharmacodynamic interaction between
Publikováno v:
Anesthesiology. 81:1371-1375
BACKGROUND Intrathecal opioids routinely are administered to surgical patients to provide prolonged postoperative analgesia. This study evaluated the dose-response effects of intrathecal fentanyl in an elderly patient population undergoing lower extr
Autor:
Robert G. Hahn, Carl-Arne Ewaldsson
Publikováno v:
Anesthesiology. 103(3)
Background In sheep, isoflurane causes extravascular accumulation of infused crystalloid fluid. The current study evaluates whether isoflurane has a greater tendency than propofol to cause extravascular retention in surgical patients. Methods Thirty
Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopy
Autor:
Michał Petelenz, Piotr Kawecki, Robert Rudner, Maciej Gonciarz, Przemysław Jałowiecki, Piotr Dziurdzik
Publikováno v:
Anesthesiology. 103(2)
Background: This study evaluated the ability of dexmedetomidine to provide analgesia and sedation for outpatient colonoscopy, examining outcomes including cardiorespiratory variables, side effects, and discharge readiness. Methods: Sixty-four patient
Autor:
John J. Savarese, Matthew R. Belmont, Martha M. Abou-Donia, Larissa Eppich, Steve Quessy, Cynthia A. Lien, Amy Abalos
Publikováno v:
Anesthesiology. 82(5)
Background Atracurium consists of a mixture of ten stereoisomers. One of these isomers, 51W89, is a potent intermediate-acting nondepolarizing neuromuscular blocking agent. Its ED95 is 0.05 mg.kg-1 in patients receiving nitrous oxide/opioid anesthesi