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Autor:
Froukje H. Knotnerus, Ernesto R R Muskiet, Martine Oostra, Jan Van Bocxlaer, Michel Struys, Maud A S Weerink, Koen Reyntjens, Pieter Colin, Clemens R M Barends
Publikováno v:
Anesthesiology, 131(5), 1004-1017. LIPPINCOTT WILLIAMS & WILKINS
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: Patients sedated with standard clinical doses of dexmedetomidine can be readily arousedDexmedetomidine doses producing mild to deep sedation lack significant analgesic effectRemifentanil is an opioid analgesic w
Autor:
Jennifer H. Walsh, Malin Jonsson Fagerlund, Mika Scheinin, David R. Hillman, Åse Lodenius, Kathleen J. Maddison, Brad K. Lawther, Lars Eriksson, Peter R. Eastwood
Publikováno v:
Anesthesiology. 131:962-973
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Dexmedetomidine is a sedative promoted as having minimal impact on ventilatory drive or upper airway muscle activity. However, a trial rece
Publikováno v:
Anesthesiology. 124:598-607
BackgroundSedation is commonly used in neurosurgical patients but has been reported to produce transient focal neurologic dysfunction. The authors hypothesized that in patients with frontal–parietal–temporal brain tumors, focal neurologic deficit
Autor:
Jeremy M. Kahn, Andrew A. Kramer, Robert N. Sladen, Gordon D. Rubenfeld, Hannah Wunsch, Gebhard Wagener, Guohua Li
Publikováno v:
Anesthesiology. 113:386-394
Background Dexmedetomidine is a novel sedative agent that causes anxiolysis without respiratory depression in critically ill patients. We sought to examine patient and hospital variation in dexmedetomidine use and adoption patterns of dexmedetomidine
Autor:
Jack Chen, Hugh Wolfenden, Yahya Shehabi, Naomi E Hammond, Frances Bass, Peter Grant, Michelle Campbell
Publikováno v:
Anesthesiology. 111:1075-1084
Background Commonly used sedatives/analgesics can increase the risk of postoperative complications, including delirium. This double-blinded study assessed the neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine compared with
Publikováno v:
ResearcherID
Background Intravenous drugs active via gamma-aminobutyric acid receptors to produce memory impairment during conscious sedation. Memory function was assessed using event-related potentials (ERPs) while drug was present. Methods The continuous recogn
Publikováno v:
Anesthesiology. 100(6)
Background Propofol is commonly used to anesthetize children undergoing esophagogastroduodenoscopy. Opioids are often used in combination with propofol to provide total intravenous anesthesia. Because both propofol and remifentanil are associated wit
Autor:
John M. Wo, Alparslan Turan, Daniel I. Sessler, Stefan Rauch, Jarrod E. Dalton, Yusuke Kasuya, Ozan Akça, Raghavendra Govinda
Publikováno v:
Anesthesiology. :1
Background Many anesthetics reduce lower esophageal sphincter pressure (LESP). Reduced pressure and consequent reduction in the gastroesophageal pressure gradient (GEPG) thus promotes gastroesophageal reflux and may contribute to aspiration pneumonia