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Autor:
Steven Mcguigan, Will Woods, David T. J. Liley, Suresh D. Muthukumaraswamy, Levin Kuhlmann, Andria Pelentritou, John R. Cormack
Publikováno v:
Anesthesiology. 132:1017-1033
Background Investigations of the electrophysiology of gaseous anesthetics xenon and nitrous oxide are limited revealing inconsistent frequency-dependent alterations in spectral power and functional connectivity. Here, the authors describe the effects
Autor:
Froukje H. Knotnerus, Ernesto R R Muskiet, Martine Oostra, Jan Van Bocxlaer, Michel Struys, Maud A S Weerink, Koen Reyntjens, Pieter Colin, Clemens R M Barends
Publikováno v:
Anesthesiology, 131(5), 1004-1017. LIPPINCOTT WILLIAMS & WILKINS
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: Patients sedated with standard clinical doses of dexmedetomidine can be readily arousedDexmedetomidine doses producing mild to deep sedation lack significant analgesic effectRemifentanil is an opioid analgesic w
Autor:
Jennifer H. Walsh, Malin Jonsson Fagerlund, Mika Scheinin, David R. Hillman, Åse Lodenius, Kathleen J. Maddison, Brad K. Lawther, Lars Eriksson, Peter R. Eastwood
Publikováno v:
Anesthesiology. 131:962-973
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Dexmedetomidine is a sedative promoted as having minimal impact on ventilatory drive or upper airway muscle activity. However, a trial rece
Autor:
Martin Luginbühl, Laura N. Hannivoort, Michel Struys, Hugo Vereecke, Johannes H. Proost, Bjorn Heyse, Douglas J. Eleveld
Publikováno v:
Anesthesiology. 120:1390-1399
Background: The authors studied the interaction between sevoflurane and remifentanil on bispectral index (BIS), state entropy (SE), response entropy (RE), Composite Variability Index, and Surgical Pleth Index, by using a response surface methodology.
Autor:
Gary W. Donaldson, Barbara A. Coda, R. Schaffer, J. Tschanz, D. J. Pavlin, Q. Nguyen, Robert Jacobson, Danny D. Shen, C. R. Chapman
Publikováno v:
Anesthesiology. 84:23-37
Background Propofol and alfentanil frequently are administered together for intravenous sedation. This study investigated pharmacokinetic and pharmacodynamic interactions between propofol and alfentanil, at sedative concentrations, with specific rega
Autor:
J. Lance Lichtor, Richard S. Finn, B Glosten, David C. Flemming, Jeffrey L. Apfelbaum, A. Uitvlugt, James P. Zacny, Dennis W. Coalson
Publikováno v:
Anesthesiology. 76:696-702
Propofol is increasingly being used in medical and surgical procedures in which conscious sedation of the patient is desired. The mood-altering and psychomotor effects of subanesthetic concentrations of propofol have not been well characterized. Ther
Autor:
John M. Wo, Alparslan Turan, Daniel I. Sessler, Stefan Rauch, Jarrod E. Dalton, Yusuke Kasuya, Ozan Akça, Raghavendra Govinda
Publikováno v:
Anesthesiology. :1
Background Many anesthetics reduce lower esophageal sphincter pressure (LESP). Reduced pressure and consequent reduction in the gastroesophageal pressure gradient (GEPG) thus promotes gastroesophageal reflux and may contribute to aspiration pneumonia