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Autor:
Elon H. Mehr, Karen S. Lindeman
Publikováno v:
Anesthesiology. 79:290-298
BACKGROUND General anesthetics modify airway responsiveness by several mechanisms, including direct effects on airway smooth muscle and reductions in neural reflex activity. Halothane has been shown to reduce responsiveness through both of these mech
Autor:
Carol A. Hirshman, Joseph D. Tobias
Publikováno v:
Anesthesiology. 72:105-110
The effect of albuterol (a beta 2 specific adrenergic agonist) on airway reactivity to histamine aerosol challenge was evaluated during halothane anesthesia and thiopental-fentanyl anesthesia in five Basenji Greyhound dogs. Responses to histamine aer
Autor:
Jaime Diaz, Cynthia A. Lien, Karen B. Wolf, Richard S. Matteo, Eugene Ornstein, Noeleen Ostapkovich
Publikováno v:
Anesthesiology. 84(3)
Background Cisatracurium, one of ten stereoisomers that comprise atracurium, is more potent than atracurium and has less propensity to release histamine. This study compares the pharmacokinetics and pharmacodynamics of cisatracurium in elderly and yo
Publikováno v:
Anesthesiology. 77:A955
Study Objectives: To determine the neuromuscular, cardiovascular, and histamine-releasing properties of doxacurium and pipecuronium at three times effective ED 95 doses (3XED 95 ). Design: Prospective, randomized clinical trial of adult patients. Set
Autor:
Jerrold H. Levy, Bruce F. Walker, John S. Ziegler, Art Shearin, David M. Adelson, Carl C. Hug, Nell W. Brister
Publikováno v:
Anesthesiology. 70:756-760
Certain opioids release histamine from cutaneous mast cells to produce local wheal and flare responses and adverse hemodynamic effects. In vivo responses to opioids suggest that cutaneous responses result from the interaction of opioids with opioid r
Publikováno v:
Anesthesiology. 55:19-25
The administration of d-tubocurarine (dTc) to animals and humans has been reported to produce hypotension. Experiments in animals suggest that the hypotension is a result of both ganglionic blockade and histamine release. In order to determine the ro
Publikováno v:
Anesthesiology. 60(5)
Publikováno v:
Anesthesiology. 71(5)
The effects of aminophylline on the release of endogenous catecholamines and on airway reactivity to aerosol histamine challenge were evaluated during halothane and thiopental/fentanyl anesthesia in basenji-greyhound dogs. Responses to histamine aero
Publikováno v:
Anesthesiology. 62(2)
Human leukocyte and skin mast cell preparations were incubated with morphine sulfate in concentrations ranging from 1.5 X 10(-5) M to 4.5 X 10(-3) M. Skin mast cells also were incubated with oxymorphone and fentanyl in the same concentrations. Human
Autor:
Yoshio Hatano, Noboru Toda
Publikováno v:
Anesthesiology. 53(2)
The effects of fentanyl on airway smooth muscle are not known. In this report the authors compare the effects of fentanyl and morphine on isolated canine tracheal smooth muscle. The contractile response of tracheal muscle strips to transmural electri