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Autor:
Kanwaljeet J. S. Anand
Publikováno v:
Anesthesiology. 131(2)
Randomised Trial of Fentanyl Anesthesia in Preterm Babies Undergoing Surgery: Effects on the Stress Response. By Anand KJ, Sippell WG, and Aynsley-Green A. Lancet 1987; 1:243–8. Reprinted with permission.In a randomised controlled trial, preterm ba
Autor:
John R. Lynch, David S. Warner, Maria Moldovan, Robert D. Pearlstein, Hazem Elsersy, Huaxin Sheng
Publikováno v:
Anesthesiology. 100:1160-1166
Background This study examined long-term outcome from severe forebrain ischemia in the rat, as a function of anesthetic given during the ischemic injury. Methods Rats were subjected to 10 min of near-complete forebrain ischemia while anesthetized wit
Publikováno v:
Anesthesiology. 81:1264-1269
BACKGROUND It has been postulated that nitric oxide (NO) is a neurotransmitter involved in consciousness, analgesia, and anesthesia. Halothane has been shown to attenuate NO-mediated cyclic guanosine monophosphate accumulation in neurons, and a varie
Autor:
Ronald F. Albrecht, Eberhard Kochs, Dale A. Pelligrino, Jochem Schulte am Esch, Christian Werner, William E. Hoffman
Publikováno v:
Anesthesiology. 76:755-762
Central neuroexcitatory receptors (N-methyl-D-aspartate [NMDA], non-NMDA) may affect outcome from cerebral ischemia by altering sympathetic nervous system activity. We tested whether ketamine, an NMDA antagonist, and NBQX, a non-NMDA antagonist, impr
Publikováno v:
Anesthesiology. 74(3)
Thirty-eight healthy outpatients undergoing elective surgical procedures lasting 1-3 h were randomly assigned to receive either desflurane 3% (approximately 0.5 MAC) or isoflurane 0.6% (approximately 0.5 MAC) for maintenance of general anesthesia wit
Autor:
Karen Dunn, Barbara McNulty, G. David Rudd, Robert J. Fragen, Jeffrey A. Katz, Colin A. Shanks
Publikováno v:
Anesthesiology. 70:432-436
In a two-part study, the dose-response relationships of doxacurium chloride (BW A938U) were evaluated during general anesthesia maintained with commonly used anesthetic techniques. In part 1, cumulative dose-response methodology was used to establish
Autor:
William E. Bunney, Michel Dubois, Thomas E. Macnamara, David Pickar, Prasad Gadde, Martin R. Cohen
Publikováno v:
Anesthesiology. 57(6)
Beta-endorphin appears to play a definite role in the biologic response to stress and in the endogenous mechanism of pain perception. Opiates exogenously administered during surgery decrease or even suppress the activation of "stress hormones" such a