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Publikováno v:
Anesthesiology. 96(5)
Background Postoperative nausea and vomiting (PONV) is still common, especially among female patients. Our hypothesis is that coinduction with clonidine reduces the incidence of PONV in adult patients undergoing breast cancer surgery. Methods Sixty-e
Autor:
Jaime Diaz, Cynthia A. Lien, Karen B. Wolf, Richard S. Matteo, Eugene Ornstein, Noeleen Ostapkovich
Publikováno v:
Anesthesiology. 84(3)
Background Cisatracurium, one of ten stereoisomers that comprise atracurium, is more potent than atracurium and has less propensity to release histamine. This study compares the pharmacokinetics and pharmacodynamics of cisatracurium in elderly and yo
Autor:
Matthew R. Belmont, John J. Savarese, Cynthia A. Lien, Virginia D. Schmith, Amy Abalos, David F. Kisor
Publikováno v:
Anesthesiology. 84(2)
Background Cisatracurium, one of the ten isomers in atracurium, is a nondepolarizing muscle relaxant with an intermediate duration of action. It is more potent and less likely to release histamine than atracurium. As one of the isomers composing atra
Publikováno v:
Anesthesiology. 71:62-68
The first pass uptake of fentanyl in the human lung was studied in two groups of patients using a double indicator dilution technique. A bolus containing fentanyl and indocyanine green dye (ICG) was rapidly injected into the central venous catheter o
Autor:
Karen Dunn, Barbara McNulty, G. David Rudd, Robert J. Fragen, Jeffrey A. Katz, Colin A. Shanks
Publikováno v:
Anesthesiology. 70:432-436
In a two-part study, the dose-response relationships of doxacurium chloride (BW A938U) were evaluated during general anesthesia maintained with commonly used anesthetic techniques. In part 1, cumulative dose-response methodology was used to establish
Autor:
Edmond I. Eger, Bradford A. Paulson, John W. Severinghaus, Ronald D. Miller, Lawrence D. Becker
Publikováno v:
Anesthesiology. 44(4)
Either fentanyl or Innovar (fentanyl, 0.05 mg/ml, and droperidol 2.5 mg/ml) was administered to supplement nitrous oxide anesthesia for operations on 29 patients. Both fentanyl and Innovar depressed the slope of the rebreathing CO2 response curve dur
Publikováno v:
Anesthesiology. 60(5)
Autor:
Mark M. Mitchell, O. Prakash, Evert N. R. Rulf, Michael K. Cahalan, Marc E. R. M. van Daele, Jos R.T.C. Roelandt
Publikováno v:
Anesthesiology. 71(4)
Despite evidence from animal experiments to the contrary, nitrous oxide (N2O) reportedly does not induce myocardial ischemia when used as an adjunct to fentanyl anesthesia in patients with coronary artery disease who have well-preserved left ventricu
Autor:
Miyao J, Sameshima T, Hiroshi Matsuura, Nozomu Yoshimura, Shigeo Baba, Takenori Miyawaki, Tsuyoshi Goromaru, Takashi Furuta
Publikováno v:
Anesthesiology. 61(1)
Although fentanyl has been used widely as a short-acting narcotic analgesic, its metabolism in humans has not been clarified. In this study, three fentanyl metabolites were identified in the urine of eight surgical patients receiving 0.3-0.5 mg of fe
Autor:
David L. Roerig, Karel J. Kotrly, Eduards J. Vucins, John P. Kampine, Christopher A. Dawson, Susan B. Ahlf
Publikováno v:
Anesthesiology. 67(4)
The first pass uptake of fentanyl, meperidine, and morphine in human lung was studied in patients using a double indicator dilution technique. A bolus containing one of the drugs and indocyanine green dye (ICG) was rapidly injected into the central v