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Autor:
Paul A. Sloan, Raeford E. Brown
Publikováno v:
Anesthesia & Analgesia. 125:1432-1434
Opioids for the treatment of acute pain and the pain of malignancy have been strongly encouraged for more than 25 years.1 In the past 2 decades, the treatment of chronic noncancer pain using long-term opioid therapy has become more common. However, r
Publikováno v:
Anesthesia & Analgesia. 125:904-906
Phenylephrine infusions are considered as standard management for obstetric spinal hypotension, but there remains reluctance to implement them in resource-limited contexts. This prospective, alternating intervention study of patients undergoing elect
Publikováno v:
Anesthesia & Analgesia. 122:1377-1384
BACKGROUND Phosphoinositide-3-kinase (PI3K)/protein kinase B (Akt) pathway activation may promote neuronal survival via neuroprotection during inflammation after cerebral ischemia. In this study, we investigated whether IV pretreatment with emulsifie
Autor:
Felice Su, Susan C. Nicolson, MaryAnn DiLiberto, Alanna S. Ocampo-Pelland, Marc R. Gastonguay, Athena F. Zuppa
Publikováno v:
Anesthesia & Analgesia. 122:1556-1566
Dexmedetomidine is a highly selective α2-agonist with hypnotic, analgesic, and anxiolytic properties. Despite off-label administration, dexmedetomidine has found a niche in critically ill neonates and infants with congenital heart disease because of
Publikováno v:
Anesthesia & Analgesia. 122:1508-1515
Postpartum hemorrhage secondary to uterine atony is a leading cause of maternal morbidity. Prolonged exposure to oxytocin for labor augmentation can result in the desensitization phenomenon, a decrease in the responsiveness of myometrium to further o
Publikováno v:
Anesthesia & Analgesia. 122:1360-1369
BACKGROUND: High systemic lidocaine concentrations exert well-known toxic effects on the central nervous system (CNS), including seizures, coma, and death. The underlying mechanisms are still largely obscure, and the actions of lidocaine on supraspin
Autor:
Antonio Castellanos-Olivares, María Esther Ocharan-Hernández, Dulce María Rascón-Martínez, Ana Fresán-Orellana, Jorge H. Genis-Zarate
Publikováno v:
Anesthesia & Analgesia. 122:969-975
Acute postoperative cognitive dysfunction is characterized by neurocognitive dysfunction and confusion. In this study, we compared the cognitive status of a geriatric population undergoing ophthalmic surgery, as assessed by the Short Portable Mental
Autor:
Nivaldo Ribeiro Villela, Cynthia S. Samary, Raquel S. Santos, Cintia L. Santos, Vinicius C. M. Cavalcanti, Mariana M. P. N. Araújo, Lígia de A. Maia, Paolo Pelosi, Patricia R. M. Rocco, Isis Hara Trevenzoli, Pedro L. Silva, Fátima Carneiro Fernandes, Luciana Boavista Barros Heil, Hananda A Poggio
Publikováno v:
Anesthesia & Analgesia. 122:1015-1023
Administering anesthetics to the obese population requires caution because of a variety of reasons including possible interactions with the inflammatory process observed in obese patients. Propofol and dexmedetomidine have protective effects on pulmo
Publikováno v:
Anesthesia & Analgesia. 122:843-856
Complex regional pain syndrome (CRPS) remains a challenging clinical pain condition. Multidisciplinary approaches have been advocated for managing CRPS. Compared with spinal cord stimulation and intrathecal targeted therapy, IV treatments are less in
Publikováno v:
Anesthesia & Analgesia. 122:698-705
Background Inhaled induction with spontaneous respiration is a technique used for difficult airways. One of the proposed advantages is if airway patency is lost, the anesthetic agent will spontaneously redistribute until anesthetic depth is reduced a