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Autor:
Jaewoong Jung, Woohyun Jung, Bon Sung Koo, Jun Chul Chung, Sang-Hyun Kim, Yang Hoon Chung, Eun Young Ko
Publikováno v:
Anesthesia & Analgesia. 133:1624-1632
BACKGROUND Previous research has not evaluated the potential effect of transversus abdominis plane (TAP) block on quality of recovery following laparoscopic cholecystectomy. Therefore, we investigated whether addition of the bilateral subcostal and l
Autor:
Alexander Tsodikov, Joseph Brooks, Graciela Mentz, Michael S. Avidan, Giancarlo Vanini, Duan Li, Daniel J. Clauw, Phillip E. Vlisides, Aleda Leis, Amy M. McKinney, Mackenzie Zierau, Jacqueline Ragheb, George A. Mashour
Publikováno v:
Anesth Analg
Background Surgical patients are vulnerable to opioid dependency and related risks. Clinical-translational data suggest that caffeine may enhance postoperative analgesia. This trial tested the hypothesis that intraoperative caffeine would reduce post
Autor:
Nikolaus Gravenstein, Ling-Sha Ju, Ning Xu, Yunan Lin, Anatoly E. Martynyuk, Jian-Jun Yang, Lei Lei, Timothy E. Morey
Publikováno v:
Anesth Analg
Background Neonatal exposure to sevoflurane induces neurobehavioral and neuroendocrine abnormalities in exposed male rats (generation F0) and neurobehavioral, but not neuroendocrine, abnormalities in their male, but not female, offspring (generation
Publikováno v:
Anesthesia & Analgesia. 130:e67-e70
Gene variants may contribute to individual differences in the experience of pain and the efficacy and reward of treatments. We explored gene variation in opioid-naïve and opioid-consuming patients undergoing elective lower extremity total joint repl
Autor:
Mariana Gobbo Braz, Chung-Yen Chen, Nayara M. Arruda, Kátina M. Souza, Lídia Raquel de Carvalho, José Reinaldo Cerqueira Braz, Aline G. Aun, Flávia R. Nogueira, Leandro Gobbo Braz
Publikováno v:
Anesthesia & Analgesia. 126:1198-1205
Little is known about the effects of desflurane associated or not with nitrous oxide (N2O) on oxidative stress and patient genetic material. The aim of this study was to compare the effects of anesthesia maintained with desflurane associated or not w
Publikováno v:
Anesthesia & Analgesia. 123:877-883
BACKGROUND The neuroactive steroid allopregnanolone (ALLO) is an endogenous allosteric modulator of γ-aminobutyric acid type A (GABAA) receptors. There is evidence that ALLO, at physiologically relevant concentrations, modulates GABAA receptor funct
Publikováno v:
Anesthesia & Analgesia. 122:996-1006
Reducing fresh gas flow (FGF) during general anesthesia reduces costs by decreasing the consumption of volatile anesthetics and attenuates their contribution to greenhouse gas pollution of the environment. The sevoflurane FGF recommendations in the F
Publikováno v:
Anesthesia & Analgesia. 122:1008-1014
Methoxycarbonyl etomidate (MOC-etomidate) and cyclopropyl methoxycarbonyl metomidate (CPMM) are rapidly metabolized "soft" etomidate analogs. CPMM's duration of hypnotic effect is context insensitive, whereas MOC-etomidate's is not. In this study, we
Autor:
Yahya I. Asiri, Bernard A. MacLeod, Stephan K. W. Schwarz, Ryan A. Whitehead, Ernest Puil, Timothy Fung
Publikováno v:
Anesthesia & Analgesia. 121:1481-1487
BACKGROUND The combination of propofol and an opioid analgesic is widely used for procedural sedation, as well as total IV anesthesia. However, opioids produce respiratory depression, a primary cause of death due to these agents. We recently reported
Autor:
Felix Ulbrich, Helen Engelstaedter, Ulrich Goebel, Volker Auwaerter, Nils Schallner, Julia Biermann, Torsten Loop
Publikováno v:
Anesthesia & Analgesia. 119:1429-1441
BACKGROUND: General anesthesia in patients with or at risk for neuronal injury remains challenging due to the controversial influence of volatile anesthetics on neuronal damage. We hypothesized that isoflurane, sevoflurane, and desflurane would exert