Zobrazeno 1 - 9
of 9
pro vyhledávání: '"785"'
Publikováno v:
Analytical Chemistry. 94:4635-4642
Rapid identification of microorganisms is clinically meaningful, and it helps to decelerate the spread of drug resistance and improve patient treatment. In this study, we present a rapid fiber probe-based Raman technique with an excitation wavelength
Autor:
Chih Chia Huang, Chun In Cheung, Tsung-Ju Li, Yao-Tzu Yang, Chien-Wei Lee, Mei-Yi Liao, I-Ling Hsu, Ting-Yu Cheng, Yi-Chun Chiu, Hsiao-Chien Chen, Yu-Cheng Chin, Wen-Jeng Wu
Publikováno v:
Analytical Chemistry. 91:8213-8220
The discovery of different binding receptors to allow rapid and high-sensitivity detection via a noninvasive urine test has become the goal for urothelial carcinoma (UC) diagnosis and surveillance. In this study, we developed a new screening membrane
Autor:
Ping Wu, Chenxin Cai, Yingfang Xing, Erjin Zheng, Xiaojun Luo, Tuli Kang, Lijuan Jiang, Qiuming Yu
Publikováno v:
Analytical Chemistry. 91:7304-7312
Epigenetic modifications of DNA are known to modulate gene activity and expression and are believed to result in genetic diseases, such as cancer. Four modified cytosines were discovered in mammalian genomes: 5-methycytoine (5mC), 5-hydroxymethylcyto
Publikováno v:
Analytical chemistry. 93(2)
This work reports a plasmonic surface-enhanced Raman scattering (SERS) biosensor that allows for quantitative analysis of hematin in erythrocytes without the need of separating it from hemoglobin (Hb). The biosensor exploits the tunable localized sur
Autor:
Zhiwei Huang, Jian-Lin Ren, Hongzhi Xu, Ming Teh, Kan Lin, Wei Zheng, Mads Sylvest Bergholt, Jianfeng Wang, Khek Yu Ho, Khay Guan Yeoh
Publikováno v:
Analytical Chemistry. 87:960-966
This study aims to characterize the in vivo Raman spectroscopic properties of normal colorectal tissues and to assess distinctive biomolecular variations of different anatomical locations in the colorectum for cancer diagnosis. We have developed a no
Publikováno v:
Analytical Chemistry. 85:11297-11303
We report a novel method making use of multivariate reference signals of fused silica and sapphire Raman signals generated from a ball-lens fiber-optic Raman probe for quantitative analysis of in vivo tissue Raman measurements in real time. Partial l
Publikováno v:
Analytical Chemistry. 81:8908-8915
Raman spectroscopy is a vibrational spectroscopic technique capable of optically probing the biomolecular changes associated with neoplastic transformation. The purpose of this study was to apply near-infrared (NIR) Raman spectroscopy in the high wav
Publikováno v:
Analytical chemistry. 87(13)
At present, tumor diagnostic imaging is commonly based on hematoxylin and eosin or immunohistochemical staining of biopsies, which requires tissue excision, fixation, and staining with exogenous marker molecules. Here, we report on label-free tumor i
Autor:
Søren Hassing, Henrik J. Ditzel, Christoph Krafft, Martin A.B. Hedegaard, Lene E. Johansen, Jiirgen Popp
Publikováno v:
Hedegaard, M, Krafft, C, Ditzel, H J, Johansen, L E, Hassing, S & Popp, J 2010, ' Discriminating isogenic cancer cells and identifying altered unsaturated fatty acid content as associated with metastasis status, using k-means clustering and partial least squares-discriminant analysis of Raman maps ', Analytical Chemistry, vol. 82, no. 7, pp. 2797-802 . https://doi.org/10.1021/ac902717d
Raman spectroscopy is a label-free, real-time diagnostic tool that shows great promise in identifying cell differences. We have evaluated the discriminatory power of Raman spectroscopy using a unique model system consisting of two isogenic cancer cel