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pro vyhledávání: '"Yuguo Tang"'
Publikováno v:
Analytical chemistry. 94(28)
A three-dimensional DNA tetrahedral nanostructure is constructed to support a walker strand on top and multiple track strands around it via the assembly of triplex-forming oligonucleotide (TFO). This design facilitates the regeneration of the sensing
Publikováno v:
Analytical chemistry. 94(6)
Circulating tumor DNA (ctDNA) serves as a powerful noninvasive and viable biomarker for the diagnosis of cancers. The abundance of ctDNA in patients with advanced stages is significantly higher than that in patients with early stages. Herein, a ratio
Autor:
Yuguo Tang, Peng Miao
Publikováno v:
Analytical Chemistry. 92:12700-12709
Messenger RNA (mRNA) is a type of important gene regulation element and reliable biomarker for the early diagnosis of diseases. However, mRNA analysis in live cells cannot be easily realized since conventional techniques always require procedures lik
Autor:
Peng Miao, Yuguo Tang
Publikováno v:
Analytical chemistry. 92(17)
Exosomal miRNA is an ideal source of noninvasive biomarker for the diagnosis of cancer. Sensitive and accurate analysis of exosomal miRNA plays an important role in facilitating clinical applications. Herein, we have developed a novel electrochemical
Publikováno v:
Analytical Chemistry. 90:11154-11160
miRNA has been serving as an ideal biomarker for diagnosis, prognosis, and therapy of many severe diseases. In this study, we have developed an amplified electrochemical method for miRNA detection using T7 exonuclease (exo) and copper nanoparticles (
Autor:
Yuguo Tang, Peng Miao
Publikováno v:
Analytical chemistry. 91(23)
Sensitive and accurate quantification of circulating tumor cell (CTC) can provide new insights for early diagnosis and prognosis of cancers. Herein, we have developed a multipedal DNA walker for ultrasensitive detection of CTC for the first time. Gen
Publikováno v:
Analytical chemistry. 88(15)
Dysregulation of miRNA expression is correlated with the development and progression of many diseases. These miRNAs are regarded as promising biomarkers. However, it is challenging to measure these low abundant molecules without employing time-consum