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Autor:
Jiayu Wan, Shengjun Bu, Xiuxia He, Xiu Liu, Hongguo Wei, Jingqi Feng, Ze Wang, Xue Li, Hongyu Zhou
Publikováno v:
Analytical and Bioanalytical Chemistry
In this study, Lba Cas12a (Cpf1) as one of the CRISPR systems from Lachnospiraceae bacterium was coupled with a hybridization chain reaction (HCR) to develop an electrochemical biosensor for detecting the pathogenic bacterium, Salmonella typhimurium.
Publikováno v:
Analytical and Bioanalytical Chemistry
Tuberculosis (TB) is one of the main infectious diseases worldwide and accounts for many deaths. It is caused by Mycobacterium tuberculosis usually affecting the lungs of patients. Early diagnosis and treatment are essential to control the TB epidemi
Publikováno v:
Analytical and Bioanalytical Chemistry
Structural determination of N-glycans by mass spectrometry is ideally performed by negative ion collision-induced dissociation because the spectra are dominated by cross-ring fragments leading to ions that reveal structural details not available by m
Publikováno v:
Analytical and Bioanalytical Chemistry
Graphical abstract Antibodies are widely employed as biorecognition elements for the detection of a plethora of compounds including food and environmental contaminants, biomarkers, or illicit drugs. They are also applied in therapeutics for the treat
Publikováno v:
Analytical and Bioanalytical Chemistry
Graphical abstract The use of magnetic beads bio-functionalized by antibodies (Ab) is constantly increasing with a wide range of biomedical applications. However, despite an urgent need for current methods to monitor Ab’s grafting process and orien
Autor:
Torsten Frosch, Swatantar Kumar, Annika Blohm, Andreas Knebl, Kirsten Küsel, Martina Herrmann, Jürgen Popp
Publikováno v:
Analytical and Bioanalytical Chemistry
Human activities have greatly increased the input of reactive nitrogen species into the environment and disturbed the balance of the global N cycle. This imbalance may be offset by bacterial denitrification, an important process in maintaining the ec
Autor:
Sultana Akter, Urpo Lamminmäki
Publikováno v:
Analytical and Bioanalytical Chemistry
Simple and rapid methods are required for screening and analysis of water samples to detect cyanobacterial cyclic peptide hepatotoxins: microcystin/nodularin. Previously, we reported a highly sensitive non-competitive heterogeneous assay for microcys
Autor:
Sebastian Ulrich, Johannes Köck, Manfred Gareis, Ludwig Niessen, Karin Schwaiger, Christoph Gottschalk
Publikováno v:
Analytical and Bioanalytical Chemistry
Cytotoxic macrocyclic trichothecenes such as satratoxins are produced by chemotype S strains of Stachybotrys chartarum. Diseases such as stachybotryotoxicosis in animals and the sick building syndrome as a multifactorial disease complex in humans hav
Publikováno v:
Analytical and Bioanalytical Chemistry
Graphical abstract During epidemics, such as the frequent and devastating Ebola virus outbreaks that have historically plagued regions of Africa, serological surveillance efforts are critical for viral containment and the development of effective ant
Autor:
Stuart Macaulay, Pavel Kulich, Alena Vrablikova, Dierk Roessner, Renata Hezova, František Hubatka, Jaroslav Turánek, Milan Raska, Jan Kotouček, Ivan Psikal
Publikováno v:
Analytical and Bioanalytical Chemistry
Porcine circovirus causes the post-weaning multi-systemic wasting syndrome. Despite the existence of commercial vaccines, the development of more effective and cheaper vaccines is expected. The usage of chimeric antigens allows serological differenti