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Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1528-R1537
Sighs, a well-known phenomenon in mammals, are substantially augmented by hypoxia and hypercapnia. Because (d-Ala2,N-Me-Phe4,Gly-ol)-enkephalin (DAMGO), a μ-receptor agonist, injected intravenously and locally in the caudal medullary raphe region (c
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1402-R1411
Neurons that immunostain for alpha-melanocyte stimulating hormone (alpha-MSH) have been identified in the nucleus ambiguus (nAmb). The presence of mRNA for melanocortin type 4 receptors (MC4Rs) has also been reported in this nucleus. On the basis of
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1124-R1131
Altered activity of the sympathetic nervous system, which innervates adipose and ovarian tissue, may play a role in polycystic ovary syndrome (PCOS). We hypothesize that electro-acupuncture (EA) and physical exercise reduce sympathetic activity by st
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1248-R1257
In response to cold and in fever, heat dissipation from the skin is reduced by sympathetic vasoconstriction. The preoptic region has been implicated in regulating basal, thermal, and febrile vasoconstriction of cutaneous vessels such as the rat's tai
Autor:
Alexander Gabor, Frans H. H. Leenen
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R618-R630
Sympathoexcitatory and hypertensive responses to central infusion of Na+-rich artificial cerebrospinal fluid (aCSF) are enhanced by aldosterone and mediated by mineralocorticoid receptors (MRs) and benzamil-blockable Na+ influx, leading to “ouabain
Autor:
Yagna P. R. Jarajapu, Prasad V. G. Katakam, Ferenc Domoki, James A. Snipes, Anna R Busija, David W. Busija
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R289-R298
Mitochondria affect cerebrovascular tone by activation of mitochondrial ATP-sensitive K+ (KATP) channels and generation of reactive oxygen species (ROS). Insulin resistance accompanying obesity causes mitochondrial dysfunction, but the consequences o
Nitric oxide modulates the cardiovascular effects elicited by acetylcholine in the NTS of awake rats
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 295:R1774-R1781
Microinjection of acetylcholine chloride (ACh) in the nucleus of the solitary tract (NTS) of awake rats caused a transient and dose-dependent hypotension and bradycardia. Because it is known that cardiovascular reflexes are affected by nitric oxide (
Autor:
Raouf A. Khalil, Wensheng Chen
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 295:R1962-R1972
Vascular resistance and blood pressure (BP) are reduced during late normal pregnancy (Norm-Preg). In contrast, studies in human preeclampsia and in animal models of hypertension in pregnancy (HTN-Preg) have suggested that localized reduction in uteri
Autor:
Rodrigo Rorato, Benedito H. Machado, Mauricio Benedetti, Margaret de Castro, José Antunes-Rodrigues, Lucila Leico Kagohara Elias
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 295:R1706-R1712
Atrial mechanoreceptors, sensitive to stretch, contribute in regulating heart rate and intravascular volume. The information from those receptors reaches the nucleus tractus solitarius and then the paraventricular nucleus (PVN), known to have a cruci
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 295:R1555-R1562
Activation of neuronal ATP-sensitive potassium (KATP) channels is an important mechanism that protects neurons and conserves neural function during hypoxia. We investigated hypoxia (bath gassed with 95% N2-5% CO2 vs. 95% O2-5% CO2 in control)-induced