Zobrazeno 1 - 10
of 125
pro vyhledávání: ''
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Psychomotor stimulants are prescribed for many medical conditions, including obesity, sleep disorders, and attention-deficit/hyperactivity disorder. However, despite their acknowledged therapeutic utility, these stimulants are frequently abused, and
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 310:R337-R345
The oxytocin (OT) and vasopressin (VP) neurons of the supraoptic nucleus (SON) demonstrate characteristics of “metabolic sensors”. They express insulin receptors and glucokinase (GK). They respond to an increase in glucose and insulin with an inc
Autor:
Reid Hayward, Traci L. Parry
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 309:R675-R683
Highly effective anthracyclines, like doxorubicin (DOX), have limited clinical use due to protracted cardiotoxic effects. While exercise is known to be cardioprotective, it is unclear whether exercise compromises chemotherapy treatment efficacy. To d
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 307:R1313-R1323
Phenylbiguanide (PBG) stimulates cardiopulmonary receptors and cardiovascular reflex responses, including decreases in blood pressure and heart rate mediated by the brain stem parasympathetic cardiac neurons in the nucleus ambiguus and nucleus tractu
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 306:R447-R456
Neurons in the supraoptic nuclei (SON) produce oxytocin and vasopressin and express insulin receptors (InsR) and glucokinase. Since oxytocin is an anorexigenic agent and glucokinase and InsR are hallmarks of cells that function as glucose and/or meta
Autor:
Lauren E. McGrath, Orianne Montaubin, Diana R. Olivos, Christopher A. Turner, Matthew R. Hayes, Elizabeth G. Mietlicki-Baase
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 306:R157-R163
Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from intestinal L-cells in response to food entering into the gastrointestinal tract. GLP-1-based pharmaceuticals improve blood glucose regulation and may hold promise for obesity treatm
Autor:
Peter Hansell, Angelica Fasching, Liselotte Pihl, Patrik Persson, Gerald F. DiBona, Fredrik Palm
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 303:R39-R47
Glomerular filtration rate (GFR) and renal blood flow (RBF) are normally kept constant via renal autoregulation. However, early diabetes results in increased GFR and the potential mechanisms are debated. Tubuloglomerular feedback (TGF) inactivation,
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 301:R783-R790
The influence of the sympathetic nervous system (SNS) upon vascular resistance is more profound in muscles comprised predominately of low-oxidative type IIB vs. high-oxidative type I fiber types. However, within muscles containing high-oxidative type
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 298:R43-R50
Insulin detemir is a novel human insulin analog that does not show the usual propensity for weight gain in diabetic patients. We speculated that this beneficial effect could be due to insulin detemir exerting stronger anorectic effects within the bra
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1402-R1411
Neurons that immunostain for alpha-melanocyte stimulating hormone (alpha-MSH) have been identified in the nucleus ambiguus (nAmb). The presence of mRNA for melanocortin type 4 receptors (MC4Rs) has also been reported in this nucleus. On the basis of