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Autor:
Urs A. Leuenberger, Jonathan Luck, Jian Cui, Cheryl Blaha, Lawrence I. Sinoway, Takuto Hamaoka
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
The effects of nitroglycerin (glyceryl trinitrate, GTN) on baroreflex sensitivity (BRS) are incompletely understood. Moreover, there are no reports evaluating the acute responses in both the sympathetic BRS (SBRS) and the cardiovagal BRS (CBRS) to th
Autor:
Thomas Christian Bonne, Tomas Ganz, Grace Jung, Andreas Breenfeldt Andersen, Elizabeta Nemeth, Nikolai Baastrup Nordsborg, Jesús R. Huertas, Jacob Bejder, Niels Vidiendal Olsen
Publikováno v:
Breenfeldt Andersen, A, Bonne, T C, Bejder, J, Jung, G, Ganz, T, Nemeth, E, Olsen, N V, Rodriguez Huertas, J & Nordsborg, N B 2021, ' Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 321, no. 2, pp. R152-R161 . https://doi.org/10.1152/ajpregu.00070.2021
Am J Physiol Regul Integr Comp Physiol
Am J Physiol Regul Integr Comp Physiol
Current markers of iron deficiency (ID) such as ferritin and hemoglobin have shortcomings, and hepcidin and erythroferrone (ERFE) could be of clinical relevance in relation to early assessment of ID. Here, we evaluate whether exposure to altitude-ind
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 321:R12-R20
Angiotensin II (ANG II) is a potent vasoconstrictor and may reduce renal blood flow (RBF), causing renal hypoxia. Hypotensive hemorrhage elevates plasma ANG II levels and is associated with increased risk of acute kidney injury. We hypothesized that
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Donepezil is a centrally acting acetylcholinesterase (AChE) inhibitor with therapeutic potential in inflammatory diseases; however, the underlying autonomic and cholinergic mechanisms remain unclear. Here, we assessed effects of donepezil on mean art
Autor:
James E. Blevins, James L. Graham, Ha Khanh Nguyen, Tami Wolden-Hanson, Mélise Marie Edwards, Adam Jay Herbertson, Peter J. Havel, Tomasz Wietecha, Andrew Dale Dodson, Kevin D. O'Brien
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
American journal of physiology. Regulatory, integrative and comparative physiology, vol 320, iss 4
American journal of physiology. Regulatory, integrative and comparative physiology, vol 320, iss 4
Previous studies indicate that oxytocin (OT) administration reduces body weight in high-fat diet (HFD)-induced obese (DIO) rodents through both reductions in food intake and increases in energy expenditure. We recently demonstrated that chronic hindb
Autor:
Simerdeep K Dhillon, Alistair J. Gunn, Laura Bennet, Tomoaki Ikeda, Shoichi Magawa, Christopher A. Lear, Yoshiki Maeda, Joanne O. Davidson, Victoria J King, Benjamin A Lear
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 319:R653-R665
Antenatal glucocorticoids improve outcomes among premature infants but are associated with hyperglycemia, which can exacerbate hypoxic-ischemic injury. It is still unclear how antenatal glucocorticoids or hyperglycemia modulate fetal cardiovascular a
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 319:R584-R591
We evaluated the hypothesis that the activation of L-type voltage-gated Ca2+ channels contributes to exercise training-induced augmentation in cholinergic sweating. On separate days, 10 habitually trained and 10 untrained men participated in two expe
Autor:
Shoichi Magawa, Alistair J. Gunn, Michael J. Beacom, Jenny A. Westgate, Tomoaki Ikeda, Laura Bennet, Christopher A. Lear
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 319:R551-R559
Circulating catecholamines are critical for fetal adaptation to hypoxia by regulating fetal heart rate (FHR) and promoting myocardial contractility and peripheral vasoconstriction. They have been hypothesized to contribute to changes in FHR variabili
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 319:R526-R540
The goal of this study was to examine the effects of systemic morphine on the pattern and morphology of gasping breathing during respiratory autoresuscitation from transient anoxia. We hypothesized that systemic morphine levels sufficient to cause si
Autor:
Michael J. Beacom, Laura Bennet, Alistair J. Gunn, Shoichi Magawa, Jenny A. Westgate, Etsuko Miyagi, Michi Kasai, Tomoaki Ikeda, Yoshiki Maeda, Christopher A. Lear
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 319:R541-R550
Fetal heart rate variability (FHRV) is a widely used index of intrapartum well being. Both arms of the autonomic system regulate FHRV under normoxic conditions in the antenatal period. However, autonomic control of FHRV during labor when the fetus is