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Autor:
Talita Rojas Sanches, José Manuel Condor Capcha, Maria Claudia Irigoyen, Margoth Ramos Garnica, Paulo Sampaio Gutierrez, Roberto de Souza Moreira, Irene L. Noronha, Lucia Andrade
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Patients undergoing coronary angiography after myocardial infarction (MI) often develop cardiac and renal dysfunction. We hypothesized that the apolipoprotein A-I mimetic peptide 4F (4F) would prevent those complications. Male Wistar rats were fed a
Autor:
David Z.I. Cherney, John D. Parker, Susanna Mak, John S. Floras, Cameron Gilbert, Andrea B. Parker, Abdul Al-Hesayen
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 310:R167-R175
Abnormal renal function is common in acute and chronic congestive heart failure (CHF) and is related to the severity of congestion. However, treatment of congestion often leads to worsening renal function. Our objective was to explore basal determina
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 305:R452-R458
Platelet P2Y12-ADP and COX-1 receptor inhibition with oral clopidogrel (CLO) and low-dose aspirin (ASA), respectively, attenuates reflex-mediated cutaneous vasodilation, but little is known about how these medications affect local vasodilatory signal
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 304:R248-R251
Prevalence of hypertension (HT) increases in women after menopause, and there is evidence that HT is not as well controlled in postmenopausal women as men. The reasons for this are not clear but may be related to the lack of adequate blockade of the
Autor:
Yusuke Ohya, Shuichi Takishita, Masanobu Yamazato, Yuji Harada, Tatsuya Tagawa, Toru Nabika, Minori Nakamoto, Atsushi Sakima
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 290:R709-R714
A chromosome 1 blood pressure quantitative trait locus (QTL) was introgressed from the stroke-prone spontaneously hypertensive rats (SHRSP) to Wistar-Kyoto (WKY) rats. This congenic strain (WKYpch1.0) showed an exaggerated pressor response to both re
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 277:R1780-R1785
The novel hypothalamic peptides orexin-A and orexin-B are known to induce feeding behavior when administered intracerebroventricularly, but little is known about other physiological functions. The renal sympathetic nerves play important roles in the
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275:R1202-R1208
The effects of 17β-estradiol (E2) on sympathetic activity were examined in conscious unrestrained ovariectomized rats, instrumented under methohexital anesthesia to record mean arterial pressure (MABP), heart rate (HR), renal nerve activity (RNA), a
Autor:
Brian J. Koos, Andrew Chau
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 274:R152-R159
CGS-21680 (CGS), a highly selective adenosine A2a receptor agonist, may excite the fetal carotid bodies. This study was designed to determine 1) whether CGS stimulates fetal breathing and 2) whether sinoaortic denervation abolishes CGS-induced tachyc
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 272:R386-R391
We investigated whether the increase in hindlimb blood flow and vascular conductance in conscious dogs during graded dynamic exercise is functionally restrained by the sympathetic nervous system. Dogs were chronically instrumented to monitor terminal
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R1264-R1269
We tested the hypothesis that sustained increases in mean arterial pressure (MAP) produce nonuniform changes in regional sympathetic nerve discharges (SND) after the return of MAP to control levels. Renal, adrenal, splanchnic, and lumbar SND were rec