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Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 301:R491-R499
Contractile reserve decreases with advancing age and chronic isoproterenol (ISO) administration is a well-characterized model of cardiac hypertrophy known to impair cardiovascular function. This study evaluated whether nonsenescent, mature adult rats
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 288:R413-R419
The aim of this study was to determine whether activation of central type II glucocorticoid receptors can blunt autonomic nervous system counterregulatory responses to subsequent hypoglycemia. Sixty conscious unrestrained Sprague-Dawley rats were stu
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 283:R1395-R1403
Birth is characterized by a surge in sympathetic outflow, heart rate (HR), mean arterial blood pressure (MABP) and circulating catecholamines. The paraventricular nucleus (PVN) of the hypothalamus is an important central regulatory site of sympatheti
Publikováno v:
Scopus-Elsevier
In response to an acute hypoxemic insult, the mammalian fetus shows a redistribution of the cardiac output in favor of the heart and brain. Peripheral vasoconstriction contributes to this response and is partly mediated by the release of catecholamin
Autor:
Aryana Zavosh, Dianne P. Figlewicz, Pam Gronbeck, Scott B. Evans, Charles W. Wilkinson, Kathy Bentson
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 281:R1426-R1436
The mechanism(s) underlying hypoglycemia-associated autonomic failure (HAAF) are unknown. To test the hypothesis that the activation of brain regions involved in the counterregulatory response to hypoglycemia is blunted with HAAF, rats were studied i
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 279:R349-R354
The current study assessed sympathetic neuronal and vasomotor responses, total body oxygen consumption, and sensory thermal perception to identify thermoregulatory differences in younger and older human subjects during core cooling. Cold fluid (40 ml
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 277:R1780-R1785
The novel hypothalamic peptides orexin-A and orexin-B are known to induce feeding behavior when administered intracerebroventricularly, but little is known about other physiological functions. The renal sympathetic nerves play important roles in the
Autor:
Yutaka Oomura, Katsuhiko Tsuchiya, Tadaomi Aikawa, Kazuo Sasaki, Itsuro Matsumoto, Akira Niijima
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275:R1003-R1012
Effects of exogenous acidic fibroblast growth factor (aFGF), which is increased in the brain by food intake, on the plasma levels of catecholamines and on sympathetic efferent outflow were examined in anesthetized rats. A guide cannula was inserted i
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275:R1279-R1286
Elevated bladder smooth muscle cell (BSMC) nerve growth factor (NGF) secretion and related neuroplasticity are associated with hyperactive voiding in spontaneously hypertensive rats (SHRs: hypertensive, behaviorally hyperactive), compared with contro
Poor relationship between arterial [lactate] and leg net release during exercise at 4,300 m altitude
Autor:
George A. Brooks, John T. Reeves, Eugene E. Wolfel, Gail E. Butterfield, Allen Cymerman, A. C. Roberts, Robert S. Mazzeo
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275:R1192-R1201
We evaluated the hypotheses that on acute exposure to hypobaric hypoxia, sympathetic stimulation leads to augmented muscle lactate production and circulating [lactate] through a β-adrenergic mechanism and that β-adrenergic adaptation to chronic hyp