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Autor:
Danforth A. Newton, Rita M. Ryan, Manjeet K. Paintlia, Demetri D. Spyropoulos, Alan H. Jobe, Matthew W. Kemp, John E. Baatz
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Atrial natriuretic peptide (ANP) and its receptors natriuretic peptide receptor (NPR)-A and NPR-C are all highly expressed in alveolar epithelial type II cells (AEC2s) in the late-gestation ovine fetal lung and are dramatically decreased postnatally.
Autor:
Ghanem, Mada, Homps-Legrand, Méline, Garnier, Marc, Morer, Lise, Goletto, Tiphaine, Frija-Masson, Justine, Wicky, Paul-Henri, Jaquet, Pierre, Bancal, Catherine, Hurtado-Nedelec, Margarita, de Chaisemartin, Luc, Jaillet, Madeleine, Mailleux, Arnaud, Quesnel, Christophe, Poté, Nicolas, Debray, Marie-Pierre, de Montmollin, Etienne, Neukirch, Catherine, Borie, Raphael, Taillé, Camille, Crestani, Bruno, Covid Cohort Study Group, French, Andréjak, Claire
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
Increased blood fibrocytes are associated with a poor prognosis in fibrotic lung diseases. We aimed to determine whether the percentage of circulating fibrocytes could be predictive of severity and prognosis during coronavirus disease 2019 (COVID-19)
Autor:
Yu-An Zhang, Johanne Pastor, Joshuah M Gagan, Orson W. Moe, Jianning Zhang, Connie C.W. Hsia, Khoa Cao, Taylor L. Davidson
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Normal lungs do not express α-Klotho (Klotho) protein but derive cytoprotection from circulating soluble Klotho. It is unclear whether chronic supranormal Klotho levels confer additional benefit. To address this, we tested the age-related effects of
Autor:
Khodr Tello, Hossein Ardeschir Ghofrani, Friedrich Grimminger, István Vadász, Robert Naeije, Manuel J. Richter, Athiththan Yogeswaran, S Harth, Faeq Husain-Syed, Werner Seeger, Henning Gall, Ryan J. Tedford, Steven Hsu
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Right ventricular (RV) function determines outcome in pulmonary arterial hypertension (PAH). RV pressure-volume loops, the gold standard for measuring RV function, are difficult to analyze. Our aim was to investigate whether simple assessments of RV
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
We have previously reported that several patients with idiopathic pulmonary hypertension (PH) had different types of G6PD deficiency. However, the role of G6PD in PH is multifactorial because G6PD is involved in controlling oxidative stress, metaboli
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
On March 11, 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19) a pandemic, and the reality of the situation has finally caught up to the widespread reach of the disease. The presentation of the disease is highly variabl
Autor:
Dusan Hanidziar, Simon C. Robson
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Oxygen is the most commonly used therapy in hospitalized patients with COVID-19. In those patients who develop worsening pneumonia and acute respiratory distress syndrome (ARDS), high concentrations of oxygen may need to be administered for prolonged
Autor:
Francisco Casado, Rory E. Morty
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 319:L854-L858
Autor:
Juan Duarte, Grégoire Manaud, Frédéric Perros, Bianca Barreira, Laura Moreno, Gema Mondejar-Parreño, Daniel Morales-Cano, María Callejo, Sergio Esquivel-Ruiz, Francisco Perez-Vizcaino, Angel Cogolludo, Miguel A Olivencia
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 319:L627-L640
Vitamin D (VitD) receptor regulates the expression of several genes involved in signaling pathways affected in pulmonary hypertension (PH). VitD deficiency is highly prevalent in PH, and low levels are associated with poor prognosis. We investigated
Autor:
Venkatachalem Sathish, Jennifer Connell, Sangeeta Bhallamudi, Christina M. Pabelick, Y. S. Prakash
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Asthma is defined as chronic inflammation of the airways and is characterized by airway remodeling, hyperresponsiveness, and acute bronchoconstriction of airway smooth muscle (ASM) cells. Clinical findings suggest a higher incidence and severity of a