Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ravinder K. Mittal"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 323:G145-G156
Esophageal peristalsis consists of initial inhibition (relaxation) followed by excitation (contraction), both of which move sequentially in the aboral direction. Initial inhibition results in receptive relaxation and bolus-induced luminal distension,
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
High-resolution esophageal manometry (HRM) in its current form assesses only the contraction phase of peristalsis. Degree of esophageal distension ahead of contraction is a surrogate of relaxation and can be measured from intraluminal esophageal impe
Autor:
Young Hoon Youn, Ali Zifan, Xinhuan Qiu, Hyun Joo Song, Ravinder K. Mittal, Melissa M. Ledgerwood-Lee
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 316:G519-G526
Each swallow induces a wave of inhibition followed by contraction in the esophagus. Unlike contraction, which can easily be measured in humans using high-resolution manometry (HRM), inhibition is difficult to measure. Luminal distension is a surrogat
Autor:
Johnny Fu, Valmik Bhargava, Ravinder K. Mittal, M. Raj Rajasekaran, My-Uyen Lilly Nguyen, Sadhana Kanoo
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 313:G581-G588
Studies show an age-related increase in the prevalence of anal incontinence and sphincter muscle atrophy. The Wnt/β-catenin signaling pathway has been recently recognized as the major molecular pathway involved in age-related skeletal muscle atrophy
Autor:
Gary G. Ghahremani, Ravinder K. Mittal, Dushyant Kumar, Erika Ruppert, Melissa M. Ledgerwood-Lee, Ali Zifan
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 313:G212-G219
The smooth muscles of the lower esophageal sphincter (LES) and skeletal muscles of the crural diaphragm (CD) provide a closure/antireflux barrier mechanism at the esophago-gastric junction (EGJ). A number of questions in regard to the pressure profil
Autor:
Ravinder K. Mittal
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 311:G431-G443
Muscularis propria throughout the entire gastrointestinal tract including the esophagus is comprised of circular and longitudinal muscle layers. Based on the studies conducted in the colon and the small intestine, for more than a century, it has been
Autor:
M. Raj Rajasekaran, Mitra Salehi, Youngjin Seo, Shantanu Sinha, Valmik Bhargava, Ravinder K. Mittal
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 307:G445-G451
Obstetrical trauma to external anal sphincter (EAS) is extremely common; however, its role in the development of anal incontinence is not clear. We examined the regenerative process and functional impact of experimental surgical trauma to EAS muscle
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 306:G505-G514
The external anal sphincter (EAS) may be injured in 25–35% of women during the first and subsequent vaginal childbirths and is likely the most common cause of anal incontinence. Since its first description almost 300 years ago, the EAS was believed
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G129-G138
The enteric nervous system of the esophagus plays an important role in its sensory and motor functions. Although the esophagus contains enteric neurons, they have never been isolated and characterized in primary culture. We isolated and cultured ente
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 303:G529-G535
We recently reported that esophageal contraction reduces esophageal wall perfusion in an animal study. Our aim was to determine esophageal wall blood perfusion (EWBP) during esophageal contraction and transient lower esophageal sphincter relaxations