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Autor:
Gregory A. Cote, Huiping Xu, Murray Korc, Laura Heathers, Samantha Deitz McElyea, Stuart Sherman, Jesse Gore
Publikováno v:
The American Journal of Gastroenterology
OBJECTIVES: Accurate peripheral markers for the diagnosis of pancreatic ductal adenocarcinoma (PDAC) are lacking. We measured the differential expression of select microRNAs (miRNAs) in plasma and bile among patients with PDAC, chronic pancreatitis (
Autor:
Jens Neumann, Petra Stieber, Rolf Lamerz, Andreas Herbst, Frank T. Kolligs, Andrea Ofner, Alexander Crispin, Alexander Philipp, Konstanze Rahmig, Andreas Jung
Publikováno v:
American Journal of Gastroenterology. 106:1110-1118
Colorectal cancer is the third most common cancer and a major cause of cancer-related deaths. Early detection of colonic lesions can reduce the incidence and mortality of colorectal cancer. Colonoscopy is the screening test for colorectal cancer with
Autor:
Hai Huang, Bo Zhang, Mu Xing Kang, Xin Dong, Jian Chen, Bin Xu, Ying Chen, Yu Lian Wu, Qiu Ping Xie
Publikováno v:
American Journal of Gastroenterology. 105:1661-1669
The prognosis of pancreatic cancer is still very poor, and the ability to detect pancreatic cancer in high-risk groups at an early stage is therefore essential for improving its long-term survival. The purpose of this study was to explore specific bi
Autor:
Yoshifumi Baba, Jeffrey A. Meyerhardt, Charles S. Fuchs, Katsuhiko Nosho, Gregory J. Kirkner, Mari Mino-Kenudson, Edward Giovannucci, Kaori Shima, Natsumi Irahara, Shuji Ogino
Publikováno v:
American Journal of Gastroenterology. 105:420-433
The number of recovered lymph nodes is associated with good prognosis among colon cancer patients undergoing surgical resection. However, little has been known on prognostic significance of lymph node count after adjusting for host immune response to
Publikováno v:
American Journal of Gastroenterology. 97:3166-3171
OBJECTIVES: Genomic instability is a driving force for tumorigenesis. Telomerase and p53 play central roles in maintaining genomic integrity. The purpose of this study was to assess the role of telomerase expression and p53 protein overexpression in
Publikováno v:
American Journal of Gastroenterology. 94:2834-2839
OBJECTIVE: Recently, an association between viral infection and the development of esophageal carcinoma has been reported, particularly the human papilloma virus (HPV) and Esptein-Bar virus (EBV). However, geographic variation in carcinogenesis is re
Autor:
Masatoshi Makuuchi, Tadatoshi Takayama, Bin Zhao, Noriaki Futakawa, Wataru Kimura, Tetsuichiro Muto, Yasushi Harihara, Keiichi Kubota
Publikováno v:
American Journal of Gastroenterology. 94:2128-2134
There have been few studies on the molecular biological characteristics of carcinoma of the papilla of Vater. In this study, p53 and p21/Waf1 expression and K-ras codon 12 mutation in carcinoma of the papilla of Vater were investigated.Thirty-seven c