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Autor:
Ramael Ohiomoba, Clyde W. Yancy, Jonathan D. Rich, Duc Thinh Pham, Quentin R. Youmans, Precious Akanyirige, Kamari Jackson, Alana D. Bryant, Ike S. Okwuosa, Allen S. Anderson, Edwin Mandieka, Ashley Ezema
Publikováno v:
American Heart Journal. 236:13-21
Amyloid cardiomyopathy (ACM) is a progressive and life-threatening disease caused by abnormal protein deposits within cardiac tissue. The most common forms of ACM are caused by immunoglobulin derived light chains (AL) and transthyretin (TTR). Orthoto
Publikováno v:
Am Heart J
BACKGROUND: Recent studies show a mechanistic link between gut microbiota-dependent formation of the atherosclerosis- and thrombosis-promoting metabolite trimethylamine N-oxide (TMAO) and cardiovascular disease (CVD). The clinical utility of TMAO in
Autor:
Gordon Jacobsen, Robert H. Christenson, Frank Peacock, James McCord, Christopher DeFilippi, Richard M. Nowak, Simon A. Mahler, Joseph Gibbs, Fred S. Apple
Publikováno v:
American Heart Journal. 227:1-8
Background Risk scores including the Thrombolysis in Myocardial Infarction (TIMI) score; History, Electrocardiogram, Age, Risk Factors, and Troponin (HEART) score; and Simplified Emergency Department Assessment of Chest Pain Score (sEDACS) have been
Autor:
Stephen L. Wasmund, Mobin Kheirkhahan, Eugene G. Kholmovski, David C. Peritz, Bosten Loveless, Gagandeep Kaur, Nassir F. Marrouche, Alan H. Morris, Ibolya Csecs, Anna Catino
Publikováno v:
American Heart Journal. 226:206-213
Introduction Endurance athletes are at higher risk for developing atrial fibrillation as compared to the general population. The exact mechanism to explain this observation is incompletely understood. Our study aimed to determine whether degree of le
Autor:
Christopher B. Granger, Guilherme D'Andréa Saba Arruda, Renata Junqueira Moll-Bernardes, Natalia Zerbinatti Salvador, Olga Ferreira de Souza, Andrea Silvestre de Souza, Denilson Campos de Albuquerque, Renato D. Lopes, John H. Alexander, Ariane Vieira Scarlatelli Macedo, Pedro Gabriel Melo de Barros e Silva, Mayara Fraga Santos, Lilian Mazza, C. Michael Gibson, Andre Feldman
Publikováno v:
American Heart Journal
Background Angiotensin-converting enzyme-2 (ACE2) may increase due to upregulation in patients using angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB). Because renin-angiotensin system blockers increase levels of
Autor:
Jacob A. Udell, Michael J. Schull, Dennis T. Ko, Maria Koh, David W.J. Armstrong, Xuesong Wang, Peter C. Austin, Geoffrey Lau, Peter A. Kavsak
Publikováno v:
American Heart Journal. 221:84-94
High-sensitivity cardiac troponin (hs-cTn) assays enhance detection of lower circulating troponin concentrations, but the impact on outcomes in clinical practice is unclear. Our objective was to compare outcomes of chest pain patients discharged from
Autor:
Jaime Hernandez-Ojeda, Roger Borràs, Georgia Sarquella-Brugada, Paloma Jordà, Elena Arbelo, Josep Brugada, Ramon Brugada, Anna Iglesias, Oscar Campuzano, Lluís Mont
Publikováno v:
American Heart Journal. 220:213-223
Cardiogenic syncope in Brugada syndrome (BrS) increases the risk of major events. Nevertheless, clinical differentiation between cardiogenic and vasovagal syncope can be challenging. We characterized the long-term incidence of major events in a large
Autor:
Anders Gabrielsen, Mikael Andersson Franko, Achim Obergfell, Tomas Jernberg, Edouard L Fu, Friedo W. Dekker, Juan Jesus Carrero
Publikováno v:
American Heart Journal, 216, 20-29. MOSBY-ELSEVIER
Background Persistent, low-grade inflammation likely participates in the pathophysiology of both atherosclerosis and kidney disease. Although high-sensitivity C-reactive protein (hsCRP) predicts future cardiovascular risk in patients with chronic kid
Autor:
M. V. Matveeva, K.R. Ratkina, O. S. Tonkikh, O.A. Oleinik, Yulia Samoilova, D.V. Podchinenova
Publikováno v:
American Heart Journal. 242:173-174
Metabolic syndrome is associated with dysmetabolic and proinflammatory pathophysiological mechanisms, which lead to cognitive impairment. Evaluation of the effect of osteopontin as a predictor of these changes with the analysis of the neuroimaging pa
Autor:
Derek P. Chew, David Brieger, Michael E. Farkouh, John K. French, Harvey D. White, Erin Morton, Stephen Quinn, Anthony Chuang, Ian A Scott, Matthew Horsfall, Kathryn Tiver, Tom Briffa, Billingsley Kaambwa, Kristina Lambrakis
Publikováno v:
American Heart Journal. 208:11-20
Background Elevated troponin level findings among patients presenting with suspected acute coronary syndrome (ACS) or another intercurrent illness undeniably identifies patients at increased risk of mortality. Whilst enhancing our capacity to discrim