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Autor:
David F. Werner, Jonathan K. Gore-Langton, Elena I. Varlinskaya, Justine D. Landin, Linda P. Spear
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Adolescent alcohol abuse can lead to behavioral dysfunction and chronic, relapsing alcohol use disorder (AUD) in adulthood. However, not all adolescents that consume alcohol will develop an AUD, therefore it is critical to identify neural
Autor:
Hongwei Liu, Seungwoo Kang, Jing Li, Danielle Gregor, Rao Fu, Wanhong Zuo, Jiang-Hong Ye, Alex Bekker, Rose Paulose, Caihong Fu, Pei Chen
Publikováno v:
Alcoholism, clinical and experimental research. 41(3)
Background Hyperalgesia or increased sensitivity to pain is often found in alcoholics during alcohol withdrawal and may contribute to relapse drinking. Alternative therapies such as acupuncture and electroacupuncture (EA), through mechanisms involvin
Publikováno v:
Alcoholism, clinical and experimental research. 40(2)
Background The aim of this study was to examine possible differences in nicotinic acetylcholine receptors and responses in rats with genetic preference or avoidance for alcohol. This was done by using 2 rat lines with high alcohol preference (Alko Al
Publikováno v:
Alcoholism, clinical and experimental research. 40(3)
Background The aversive properties of ethanol (EtOH) that limit its intake are poorly understood. There is an increasing interest in the role of the rostromedial tegmental nucleus (RMTg), because it encodes aversion signals and inhibits motivated beh
Autor:
Mauro A. M. Carai, Daniela Vargiolu, Paola Maccioni, Carla Lobina, Alessandro Zaru, Barbara Loi, Giancarlo Colombo, Gian Luigi Gessa
Publikováno v:
Alcoholism, clinical and experimental research. 38(9)
Background Recent experimental data indicate that treatment with the selective dopamine β-hydroxylase inhibitor, nepicastat, suppressed different reward-related behaviors, including self-administration of chocolate and reinstatement of cocaine and c
Publikováno v:
Alcoholism, clinical and experimental research. 38(8)
Background Methylphenidate (MPH) is a stimulant prescribed to treat attention-deficit/ hyperactivity disorder. Its primary mechanism of action is in the dopamine system, alterations of which are associated with vulnerability to alcohol abuse. There a
Autor:
Javier Fernández-Solari, Juan C. Elverdin, Pablo Nicolás Surkin, Cesar A. Ossola, Claudia E. Mohn
Publikováno v:
Alcoholism, clinical and experimental research. 38(7)
Background: The aim of this study was to assess the effects of chronic alcohol consumption on periodontitis development in rats. Methods: Periodontal disease was experimentally induced by lipopolysaccharide (LPS; 2 mg/ml) injections into the gingival
Autor:
Stephen M. Fischer, Janice C. Froehlich, Dennis D. Rasmussen, Brett J. Hausauer, David Federoff
Publikováno v:
Alcoholism, clinical and experimental research. 37(9)
Background This study examined whether prazosin reduces alcohol drinking over the course of prolonged treatment and whether it blocks the initiation of alcohol drinking in rats with a genetic predisposition toward high alcohol drinking, that is alcoh
Autor:
Edward D. Levin, Joshua E. Johnson, Cori Wells, Karen Gordon, Hannah G. Sexton, Amir H. Rezvani
Publikováno v:
Alcoholism, clinical and experimental research. 37(9)
CAFFEINE, ALCOHOL AND NICOTINE are three of the most widely used psychoactive drugs in the world. Although these drugs are often used together, the influence of caffeine on consumption of alcohol and nicotine is not fully explored. The aim of the cur
Publikováno v:
Alcoholism, clinical and experimental research. 37(4)
Background Binge drinking is defined as a pattern of alcohol drinking that brings blood alcohol levels to 80 mg/dl or above. In this study, we pharmacologically characterized the intermittent access to 20% ethanol (EtOH) model (Wise, Psychopharmacolo