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Autor:
Agueda, González-Rodríguez, Jose A, Más-Gutierrez, Mercedes, Mirasierra, Antonio, Fernandez-Pérez, Yong J, Lee, Hwi J, Ko, Jason K, Kim, Eduardo, Romanos, Jose M, Carrascosa, Manuel, Ros, Mario, Vallejo, Cristina M, Rondinone, Angela M, Valverde
Publikováno v:
Aging cell. 11(2)
Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of insulin signaling and a therapeutic target for type 2 diabetes (T2DM). In this study, we have evaluated the role of PTP1B in the development of aging-associated obesity, inflammation,